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1.
公开(公告)号:US20120009212A1
公开(公告)日:2012-01-12
申请号:US13014664
申请日:2011-01-26
申请人: Robert S. HODGES , Kathryn V. Holmes , Zhe Yan , Wendy J. Hartsock , Zhaohui Qian , Brooke Elizabeth Bishop Hirsch
发明人: Robert S. HODGES , Kathryn V. Holmes , Zhe Yan , Wendy J. Hartsock , Zhaohui Qian , Brooke Elizabeth Bishop Hirsch
IPC分类号: A61K39/385 , A61P31/12 , A61P37/04 , C07K17/02 , C07K17/10
CPC分类号: A61K39/385 , A61K39/12 , A61K39/145 , A61K2039/55505 , A61K2039/55566 , A61K2039/6081 , A61K2039/645 , A61K2039/70 , C12N2760/16134 , C12N2760/18534 , C12N2760/18634 , C12N2760/18734 , C12N2770/20034
摘要: Templated conjugates created from naturally-occurring protein sequences found in pathogens, such as viruses, are disclosed. The sequences are “templated” into a consensus coiled-coil sequence in order to form a two-stranded antigen suitable for immunization of a subject.
摘要翻译: 公开了由病原体(例如病毒)中发现的天然存在的蛋白质序列产生的模板缀合物。 将序列“模板化”为共有卷曲螺旋序列,以形成适合于受试者免疫的双链抗原。
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公开(公告)号:US07278892B1
公开(公告)日:2007-10-09
申请号:US11676061
申请日:2007-02-16
申请人: Min-Lung Chien , Hsueh-Chih Cheng , Hong-Wei Zheng , Hong-Zhe Yan
发明人: Min-Lung Chien , Hsueh-Chih Cheng , Hong-Wei Zheng , Hong-Zhe Yan
IPC分类号: H01R4/48
CPC分类号: H01R13/2442
摘要: A connector for a battery has an insulative housing and a plurality of terminals. The insulative housing has a plurality of cavities and each cavity has a front opening and two inner sidewalls. Each inner sidewall has a rear mounting slot and a front mounting slot. The terminals correspond respectively to and are mounted respectively in the cavities and each terminal has an arm portion, a body portion and a soldering portion. The arm portion is resilient. The body portion is mounted in a corresponding cavity, is formed on the arm portion and having two wing portions mounted respectively in the rear mounting slots. The soldering portion is formed on the body portion and has two hook portions mounted respectively in the front mounting slots in the corresponding cavity. The terminal is mounted stably and securely in the corresponding cavity.
摘要翻译: 电池用连接器具有绝缘壳体和多个端子。 绝缘壳体具有多个空腔,并且每个空腔具有前开口和两个内侧壁。 每个内侧壁具有后安装槽和前安装槽。 端子分别对应于并分别安装在空腔中,并且每个端子具有臂部分,主体部分和焊接部分。 臂部分是弹性的。 主体部分安装在相应的空腔中,形成在臂部分上,并且具有分别安装在后安装槽中的两个翼部。 焊接部分形成在主体部分上,并且具有分别安装在相应空腔中的前安装槽中的两个钩部。 端子稳定且牢固地安装在相应的腔中。
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公开(公告)号:US20120014972A1
公开(公告)日:2012-01-19
申请号:US13014682
申请日:2011-01-26
申请人: Robert S. Hodges , Brooke Elizabeth Bishop Hirsch , Zhe Yan , Kathryn V. Holmes , Zhaohui Qian , Wendy Hartsock
发明人: Robert S. Hodges , Brooke Elizabeth Bishop Hirsch , Zhe Yan , Kathryn V. Holmes , Zhaohui Qian , Wendy Hartsock
CPC分类号: A61K39/385 , A61K39/12 , A61K39/145 , A61K2039/55505 , A61K2039/55566 , A61K2039/6081 , A61K2039/645 , A61K2039/70 , C12N2760/16134 , C12N2760/18534 , C12N2760/18634 , C12N2760/18734 , C12N2770/20034
摘要: The disclosure relates at least in part to embodiments of compositions and methods including vaccines for protection against multiple serologically distinct strains of influenza virus. This disclosure provides significant advances and addresses important needs in the influenza vaccine field.
摘要翻译: 本公开至少部分地涉及组合物和方法的实施方案,包括用于保护针对多种血清学不同的流感病毒株的疫苗。 本披露提供了重大进展,并解决了流感疫苗领域的重要需求。
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4.
公开(公告)号:US20140154282A1
公开(公告)日:2014-06-05
申请号:US13981300
申请日:2012-01-26
申请人: Robert S. Hodges , Kathryn V. Holmes , Zhe Yan , Wendy Jeanne Hartsock , Zhaohui Qian , Brooke Elizabeth Bishop Hirsch
发明人: Robert S. Hodges , Kathryn V. Holmes , Zhe Yan , Wendy Jeanne Hartsock , Zhaohui Qian , Brooke Elizabeth Bishop Hirsch
IPC分类号: A61K39/145
CPC分类号: A61K39/145 , A61K39/12 , A61K47/643 , A61K2039/6081 , A61K2039/64 , C12N2760/16134
摘要: Templated conjugates created from naturally-occurring protein sequences found in pathogens, such as viruses, are disclosed. The sequences are “templated” into a consensus coiled-coil sequence in a platform in order to form a two-stranded antigen suitable for immunization of a subject.
摘要翻译: 公开了由病原体(例如病毒)中发现的天然存在的蛋白质序列产生的模板缀合物。 将序列“模板化”成平台中的共有卷曲螺旋序列,以形成适合于受试者免疫的双链抗原。
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