公开(公告)号：US20150376605A1

公开(公告)日：2015-12-31

申请号：US14752602

申请日：2015-06-26

Applicant: 10X Genomics, Inc.

Inventor： Mirna Jarosz ,  Christopher Hindson ,  Michael Schnall-Levin ,  Kevin Dean Ness ,  Serge Saxonov ,  Benjamin Hindson ,  John Stuelpnagel

IPC: C12N15/10 ,  C12Q1/68

CPC classification number: C12N15/1058 ,  C12Q1/6806 ,  C12Q1/686 ,  C12Q2535/122 ,  C12Q2563/159 ,  C12Q2563/179

Abstract: The present disclosure relates to methods and systems for sample processing and analyzing when the total quantity of input sample is low or when a target of interest is present as a relatively minor or rare population within the overall sample. The disclosure particularly relates to analyzing nucleic acid samples, including samples where a target nucleic acid of interest is present as a relatively low proportion of the overall nucleic acids.

Abstract translation: 本公开涉及当输入样品的总量低或当感兴趣的目标作为整个样品中相对较小或罕见的群体存在时的样品处理和分析的方法和系统。 本公开特别涉及分析核酸样品，包括其中存在目的靶核酸作为总体核酸的相对低比例的样品。