公开(公告)号：US20210375392A1

公开(公告)日：2021-12-02

申请号：US17303398

申请日：2021-05-27

申请人： 23andMe, Inc.

发明人： Michael Polcari ,  Jianan Zhan ,  Manoj Ganesan ,  Austin William Marshall ,  James Rowan Ashenhurst ,  Derrick Poo-Ray Kondo ,  Shiva Amiri ,  Subarnarekha Sinha ,  Sanjeev Suresh ,  John Michael Macpherson ,  Bertram Lorenz Koelsch ,  Cordell T. Blakkan ,  Shannon M. Hamilton

IPC分类号： G16B20/20 ,  G16H50/30 ,  G16B5/00

摘要： The disclosed embodiments concern methods, apparatus, systems, and computer program products for developing polygenic risk score (PRS) models. In some implementations, a fully automated process is provided that allows for a PRS model to be defined by an initial set of parameters. In some implementations the PRS models are trained to provide a PRS for particular populations.