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公开(公告)号：US11514627B2
公开(公告)日：2022-11-29
申请号：US16948311
申请日：2020-09-11
申请人： 23andMe, Inc.
发明人： Ethan M. Jewett , Andrew C. Seaman , Kimberly F. McManus , William A. Freyman , Cordell T. Blakkan , Adam Auton , Joanna L. Mountain , Susan M. Furest , Rachel E. Lopatin , Hang Xu , Hilary M. Vance
IPC分类号： G06N20/00 , G06T11/20 , G06F3/14 , G06T11/00 , G06F3/04842 , G06N7/00 , G06N5/04 , G06F16/245 , G06F3/0481
摘要： The disclosed embodiments concern methods, apparatus, systems and computer program products for determining and displaying pedigrees based on IBD data. Some implementations use a probabilistic relationship model to obtain various likelihoods of various potential relationships based on pairwise IBD data and pairwise age data. Some implementations build large pedigrees by combining smaller pedigrees. Some implementations display pedigree graphs with various features that are informative and easy to understand.
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公开(公告)号：US11783919B2
公开(公告)日：2023-10-10
申请号：US17450417
申请日：2021-10-08
申请人： 23andMe, Inc.
发明人： Tulasi Krishna Paradarami , Michael Polcari , Yeshwanth Bashyam Balachander , Matthew Bryan Corley , Anuved Verma , Anja Bog , Cordell T. Blakkan , Dmitry Stupakov
摘要： The disclosed embodiments concern methods, apparatus, systems, and computer program products for storing and retrieving genetic data for individuals. In some implementations, a storage format is provided that allows genetic data to be defined by metadata for reproduce-ability.
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公开(公告)号：US12073495B2
公开(公告)日：2024-08-27
申请号：US17248710
申请日：2021-02-03
申请人： 23andMe, Inc.
发明人： Ethan M. Jewett , Andrew C. Seaman , Kimberly F. McManus , William Allen Freyman , Cordell T. Blakkan , Adam Auton , Joanna L. Mountain , Susan M. Furest , Rachel E. Lopatin , Hang Xu , Hilary M. Vance
IPC分类号： G06N20/00 , G06F3/0481 , G06F3/04842 , G06F3/14 , G06F16/245 , G06N5/04 , G06N7/01 , G06T11/00 , G06T11/20
CPC分类号： G06T11/206 , G06F3/0481 , G06F3/04842 , G06F3/14 , G06F16/245 , G06N5/04 , G06N7/01 , G06N20/00 , G06T11/001 , G06T11/203 , G06T2200/24
摘要： The disclosed embodiments concern methods, apparatus, systems and computer program products for determining and displaying pedigrees based on IBD data. Some implementations use a probabilistic relationship model to obtain various likelihoods of various potential relationships based on pairwise IBD data and pairwise age data. Some implementations build large pedigrees by combining smaller pedigrees. Some implementations display pedigree graphs with various features that are informative and easy to understand.
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公开(公告)号：US20220198726A1
公开(公告)日：2022-06-23
申请号：US17693245
申请日：2022-03-11
申请人： 23andMe, Inc.
发明人： Ethan Macneil Jewett , Andrew C. Seaman , Kimberly Faith McManus , William Allen Freyman , Cordell T. Blakkan , Adam Auton , Joanna Louise Mountain , Susan M. Furest , Rachel E. Lopatin , Hang Xu , Hilary M. Vance
IPC分类号： G06T11/20 , G06F3/14 , G06T11/00 , G06F3/04842 , G06N20/00 , G06N7/00 , G06N5/04 , G06F16/245 , G06F3/0481
摘要： The disclosed embodiments concern methods, apparatus, systems and computer program products for determining and displaying pedigrees based on IBD data. Some implementations use a probabilistic relationship model to obtain various likelihoods of various potential relationships based on pairwise IBD data, and pairwise age data. Some implementations build large pedigrees by combining smaller pedigrees. Some implementations display pedigree graphs with various features that are informative and easy to understand.
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公开(公告)号：US20230410948A1
公开(公告)日：2023-12-21
申请号：US18457824
申请日：2023-08-29
申请人： 23andMe, Inc.
发明人： Tulasi Krishna Paradarami , Michael Polcari , Yeshwanth Bashyam Balachander , Matthew Bryan Corley , Anuved Verma , Anja Bog , Cordell T. Blakkan , Dmitry Stupakov
摘要： The disclosed embodiments concern methods, apparatus, systems, and computer program products for storing and retrieving genetic data for individuals. In some implementations, a storage format is provided that allows genetic data to be defined by metadata for reproduce-ability.
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公开(公告)号：US20220115139A1
公开(公告)日：2022-04-14
申请号：US17450417
申请日：2021-10-08
申请人： 23andMe, Inc.
发明人： Tulasi Krishna Paradarami , Michael Polcari , Yeshwanth Bashyam Balachander , Matthew Bryan Corley , Anuved Verma , Anja Bog , Cordell T. Blakkan
摘要： The disclosed embodiments concern methods, apparatus, systems, and computer program products for storing and retrieving genetic data for individuals. In some implementations, a storage format is provided that allows genetic data to be defined by metadata for reproduce-ability.
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公开(公告)号：US20210375392A1
公开(公告)日：2021-12-02
申请号：US17303398
申请日：2021-05-27
申请人： 23andMe, Inc.
发明人： Michael Polcari , Jianan Zhan , Manoj Ganesan , Austin William Marshall , James Rowan Ashenhurst , Derrick Poo-Ray Kondo , Shiva Amiri , Subarnarekha Sinha , Sanjeev Suresh , John Michael Macpherson , Bertram Lorenz Koelsch , Cordell T. Blakkan , Shannon M. Hamilton
摘要： The disclosed embodiments concern methods, apparatus, systems, and computer program products for developing polygenic risk score (PRS) models. In some implementations, a fully automated process is provided that allows for a PRS model to be defined by an initial set of parameters. In some implementations the PRS models are trained to provide a PRS for particular populations.
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公开(公告)号：US20210166452A1
公开(公告)日：2021-06-03
申请号：US17248710
申请日：2021-02-03
申请人： 23andMe, Inc.
发明人： Ethan M. Jewett , Andrew C. Seaman , Kimberly F. McManus , William Allen Freyman , Cordell T. Blakkan , Adam Auton , Joanna L. Mountain , Susan M. Furest , Rachel E. Lopatin , Hang Xu , Hilary M. Vance
IPC分类号： G06T11/20 , G06F3/0484 , G06F3/14 , G06F16/245 , G06N20/00 , G06F3/0481 , G06N5/04 , G06N7/00 , G06T11/00
摘要： The disclosed embodiments concern methods, apparatus, systems and computer program products for determining and displaying pedigrees based on IBD data. Some implementations use a probabilistic relationship model to obtain various likelihoods of various potential relationships based on pairwise IBD data and pairwise age data. Some implementations build large pedigrees by combining smaller pedigrees. Some implementations display pedigree graphs with various features that are informative and easy to understand.
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公开(公告)号：US20210082167A1
公开(公告)日：2021-03-18
申请号：US16948311
申请日：2020-09-11
申请人： 23andMe, Inc.
发明人： Ethan M. Jewett , Andrew C. Seaman , Kimberly F. McManus , William A. Freyman , Cordell T. Blakkan , Adam Auton , Joanna L. Mountain , Susan M. Furest , Rachel E. Lopatin , Hang Xu , Hilary M. Vance
IPC分类号： G06T11/20 , G06F3/14 , G06T11/00 , G06F3/0484 , G06F3/0481 , G06N20/00 , G06N7/00 , G06N5/04 , G06F16/245
摘要： The disclosed embodiments concern methods, apparatus, systems and computer program products for determining and displaying pedigrees based on IBD data. Some implementations use a probabilistic relationship model to obtain various likelihoods of various potential relationships based on pairwise IBD data and pairwise age data. Some implementations build large pedigrees by combining smaller pedigrees. Some implementations display pedigree graphs with various features that are informative and easy to understand.
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