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    Article comprising a microneedle
    1.
    发明授权
    Article comprising a microneedle 有权

    公开(公告)号：US10201691B2

    公开(公告)日：2019-02-12

    申请号：US14904998

    申请日：2014-07-10

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： Dennis G. Berry ,  Paul A. Martinson ,  Chin-Yee Ng ,  Ryan Patrick Simmers

    IPC: A61M37/00

    Abstract: An article 100 comprising at least one microneedle 160 is provided. The article comprises a first side 112 and a second side 114 opposite the first side. The first side comprises a central cavity portion 120 and a platform portion 130, with at least one microneedle extending therefrom, wherein the platform portion is not coplanar with the central cavity portion. The platform portion substantially surrounds the central cavity portion. The at least one microneedle 160 comprises a body comprising an outer surface 163; a base segment 166 having a base and a first shape; a tip segment 168 having a tip 164 and a second shape, wherein the second shape is distinct from the first shape; a transition plane 167 that delineates the base segment and the tip segment; and a central axis.

    Hollow microneedle with beveled tip
    2.
    发明授权
    Hollow microneedle with beveled tip 有权

    公开(公告)号：US10232157B2

    公开(公告)日：2019-03-19

    申请号：US14904975

    申请日：2014-07-10

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： Dennis G. Berry ,  Paul A. Martinson ,  Ryan Patrick Simmers

    IPC: A61M37/00 ,  A61B5/15 ,  B29C45/26 ,  B29C59/02 ,  B28B1/24 ,  B29L31/00 ,  B29C67/24 ,  B29C45/00 ,  B29K69/00

    Abstract: An article having at least one microneedle (160, 260) is provided. The microneedle includes a base (162), an elongated body (161) having a central axis (130) and a body diameter (168), a tip portion (166), and a hollow channel (170). The a tip portion includes a tip (164), a first bevel face (140) oriented diagonally with respect to the central axis and extending through at least 75% of the body diameter, a second bevel face (146) oriented substantially perpendicular to the central axis and intersecting the first bevel face, and a bevel opening defined by a first edge (174) of the first bevel face and a second edge (176) of the second bevel face. The hollow channel extends axially into the body from the bevel opening (172).

    Article comprising a microneedle and methods of use
    3.
    发明授权
    Article comprising a microneedle and methods of use 有权

    公开(公告)号：US10576257B2

    公开(公告)日：2020-03-03

    申请号：US16221130

    申请日：2018-12-14

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： Dennis G. Berry ,  Paul A. Martinson ,  Chin-Yee Ng ,  Ryan Patrick Simmers

    IPC: A61M37/00

    Abstract: An article comprising at least one microneedle is provided. The article can comprises a first side and a second side opposite the first side. The first side comprises a central cavity portion and a platform portion, with at least one microneedle extending therefrom, wherein the platform portion is not coplanar with the central cavity portion. The platform portion substantially surrounds the central cavity portion. The at least one microneedle comprises a body comprising an outer surface; a base segment having a base and a first shape; a tip segment having a tip and a second shape, wherein the second shape is distinct from the first shape; a transition plane that delineates the base segment and the tip segment; and a central axis. Methods of using the article are also provided.

    Hollow microneedle array article
    4.
    发明授权
    Hollow microneedle array article 有权

    公开(公告)号：US10099043B2

    公开(公告)日：2018-10-16

    申请号：US14905018

    申请日：2014-07-10

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： Dennis G. Berry ,  Paul A. Martinson ,  Ryan Patrick Simmers

    IPC: A61M37/00 ,  A61B5/15

    Abstract: An article 100 having a first side 112 that has a central portion 130 defined by a first edge 134, a microneedle-free peripheral portion 140 that substantially surrounds the central portion, and a plurality of spaced-apart hollow microneedles 160. Each microneedle has a body that includes an outer surface 163; a base segment 166 having a base 162 and a first shape; a tip segment 168 having a tip 164 and a second shape, wherein the second shape is distinct from the first shape; a transition plane 167 that delineates the base segment and the tip segment; and a central axis 180. An angle, defined by an intersection of the central axis of at least one microneedle and a shortest line extending from the first edge and through the transition plane of the at least one microneedle, is less than about 50°.

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