公开(公告)号：US20140207101A1

公开(公告)日：2014-07-24

申请号：US14118904

申请日：2012-06-06

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Craig S. Moeckly ,  Dennis G. Berry ,  Ryan Patrick Simmers ,  Erik J. Johnson ,  Richard D. Smasal

IPC: A61M37/00

CPC classification number: A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0046 ,  A61M2037/0061

Abstract: A device and method for creating microchannels in the stratum corneum. The device includes a handle and a substrate detachably attached to the handle by a coupler. The substrate has a plurality of microstructures for creating microchannels in the stratum corneum. The substrate is detachable from the handle for disposal.

Abstract translation: 用于在角质层中产生微通道的装置和方法。 该装置包括手柄和可通过耦合器可拆卸地附接到手柄的基板。 基底具有用于在角质层中产生微通道的多个微结构。 基板可从手柄上拆下以便处理。

公开(公告)号：US10398885B2

公开(公告)日：2019-09-03

申请号：US15545029

申请日：2016-01-19

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Michael J. Frits ,  Craig S. Moeckly ,  Daniel H. Berg ,  Jerome E. Gysbers ,  Ryan Patrick Simmers

IPC: A61B5/15 ,  A61M37/00

Abstract: An article (100) comprising at least one microneedle (160) is provided. The article comprises a first side (112) and a second side (114) opposite the first side. The first side comprises a central cavity portion (120) and a platform portion (130), with at least one microneedle extending therefrom, wherein the platform portion is not coplanar with the central cavity portion. The platform portion substantially surrounds the central cavity portion. The at least one microneedle comprises a body comprising an outer surface (163); a base segment (166) having a base (162) and a first shape; a tip segment (168) having a tip and a second shape, wherein the second shape is distinct from the first shape; a transition plane (167) that delineates the base segment and the tip segment; and a central axis (180). Methods of using the article are also provided.

公开(公告)号：US20150352295A1

公开(公告)日：2015-12-10

申请号：US14759757

申请日：2014-01-07

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Scott A. Burton ,  Craig S. Moeckly ,  Ryan P. Simmers

IPC: A61M5/50 ,  A61M37/00

CPC classification number: A61M5/5086 ,  A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0046 ,  A61M2205/106

Abstract: An applicator and method for applying a microneedle device to skin. The applicator can include a housing and a reciprocating support structure slidably engaged with the housing. The reciprocating support structure can have a plurality of alignment feet. The applicator can have a lockout mechanism that prevents actuation if the alignment feet are not evenly aligned. The applicator can include a device life indicator that is capable of counting the number of use cycles that the applicator has undergone and providing feedback to the user. The applicator can include a dose timer capable of determining the time that has elapsed after actuation of the device and providing feedback to the user.

Abstract translation: 用于将微针装置施加到皮肤上的涂抹器和方法。 施加器可以包括壳体和与壳体可滑动地接合的往复运动支撑结构。 往复式支撑结构可以具有多个对准脚。 如果对准脚不均匀对准，施加器可以具有防止致动的锁定机构。 施用器可以包括能够计数施加器已经经历的使用周期数并向用户提供反馈的装置寿命指示器。 涂抹器可以包括剂量定时器，其能够确定在致动装置之后已经经过的时间并向用户提供反馈。