公开(公告)号：US20210244819A1

公开(公告)日：2021-08-12

申请号：US17242578

申请日：2021-04-28

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Joseph M. Beaurline ,  James M. Elvecrog ,  John P. Vasilakos ,  John T. Capecchi ,  Karen E. Johnson

IPC: A61K47/44 ,  A61K9/00 ,  C07D471/04 ,  A61K31/4745 ,  A61K47/10

Abstract: Injectable formulations comprising ethanol, sesame oil, and an Immune Response Modifier compound are disclosed. Methods of making the formulations and methods of using the formulations for treatment of a disease in a subject, e.g., neoplastic disease, comprising injecting the formulations into a subject hi need of treatment, are also provided.

公开(公告)号：US11020486B2

公开(公告)日：2021-06-01

申请号：US15032773

申请日：2014-10-30

Applicant: 3M Innovative Properties Company

Inventor： Joseph M. Beaurline ,  James M. Elvecrog ,  John P. Vasilakos ,  John Thomas Capecchi ,  Karen Elizabeth Johnson

IPC: A61K47/44 ,  A61K9/00 ,  C07D471/04 ,  A61K31/4745 ,  A61K47/10

Abstract: Injectable formulations comprising ethanol, sesame oil, and an Immune Response Modifier compound are disclosed. Methods of making the formulations and methods of using the formulations for treatment of a disease in a subject, e.g., neoplastic disease, comprising injecting the formulations into a subject hi need of treatment, are also provided.

公开(公告)号：US10378041B2

公开(公告)日：2019-08-13

申请号：US15002696

申请日：2016-01-21

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Wensheng Xia ,  Patrick A. Mach ,  Joseph M. Beaurline ,  Jason W. Bjork ,  Jie J. Liu

IPC: C12Q1/04 ,  C12Q1/689 ,  C12N1/14 ,  C12N1/38 ,  C12N1/20

Abstract: A latent effervescent body comprising a selective agent is disclosed. A method of using the latent effervescent body in a method to selectively enrich a target microorganism is also disclosed. The method comprises providing a sample, a culture medium, and the latent effervescent body. The method further comprises contacting the sample, the culture medium, and the latent effervescent body under conditions to facilitate growth of the target microorganism. The method further comprises releasing the selective agent from the latent effervescent body. Optionally, the method includes detecting a microorganism.