公开(公告)号：US10695289B2

公开(公告)日：2020-06-30

申请号：US15766469

申请日：2016-10-07

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Kenneth E. Brown ,  Daniel M. Dohmeier ,  Joan T. Moseman ,  Ying Zhang ,  Alan Harris ,  Gary Hattersley ,  Lisa A. Dick

IPC: A61K9/00 ,  A61K47/02 ,  A61K38/00 ,  A61B17/20 ,  A61B17/00

Abstract: A medical device comprising a composition comprising a therapeutically active amount of active agent, a zinc compound, and an array of microneedles. The zinc compound may be selected from the group consisting of zinc, pharmaceutically acceptable salts of zinc, and mixtures thereof. At least a portion of the composition is present as a coating on at least a portion of the microneedles. Methods of delivering a therapeutically active agent to a mammal using compositions of the disclosure are also included.