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公开(公告)号：US20140046293A1
公开(公告)日：2014-02-13
申请号：US13791360
申请日：2013-03-08
Applicant: Radius Health, Inc. , 3M Innovative Properties Company, a wholly owned subsidiary of 3M Company
Inventor： Gary Hattersley , Kris J. Hansen , Amy S. Determan , Ying Zhang
Abstract: The present invention provides compositions, devices, methods and processes related to the intradermal delivery of PTHrP and PTHrP analogues, particularly [Glu22,25, Leu23,28,31, Aib29, Lys26,30]hPTHrP(1-34)NH2.
Abstract translation: 本发明提供了与皮内递送PTHrP和PTHrP类似物，特别是[Glu22,25，Leu23,28,31，Aib29，Lys26,30] hPTHrP（1-34）NH2相关的组合物，装置，方法和方法。
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Patent Agency Ranking
公开(公告)号：US10695289B2
公开(公告)日：2020-06-30
申请号：US15766469
申请日：2016-10-07
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Kenneth E. Brown , Daniel M. Dohmeier , Joan T. Moseman , Ying Zhang , Alan Harris , Gary Hattersley , Lisa A. Dick
Abstract: A medical device comprising a composition comprising a therapeutically active amount of active agent, a zinc compound, and an array of microneedles. The zinc compound may be selected from the group consisting of zinc, pharmaceutically acceptable salts of zinc, and mixtures thereof. At least a portion of the composition is present as a coating on at least a portion of the microneedles. Methods of delivering a therapeutically active agent to a mammal using compositions of the disclosure are also included.
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公开(公告)号：US10568937B2
公开(公告)日：2020-02-25
申请号：US16092587
申请日：2017-04-06
Applicant: Radius Health, Inc. , 3M Innovative Properties Company
Inventor： Gary Hattersley , Alan Harris , Jamal Saeh , Ehab Hamed , Kenneth Brown , Daniel Dohmeier , Joan Moseman , Ying Zhang , Lisa Dick
Abstract: Disclosed are abaloparatide formulations for transdermal delivery of a therapeutically effective amount of abaloparatide, as well as transdermal patches prepared using these formulations, methods of preparing the disclosed formulations and patches, and methods of using these formulations and patches to treat osteoporosis, osteopenia, osteoarthritis, and/or bone fracture, improve bone mineral density (BMD), improve trabecular bone score (TBS), and treat, prevent, and/or reduce bone fractures.
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公开(公告)号：US20200164045A1
公开(公告)日：2020-05-28
申请号：US16733779
申请日：2020-01-03
Applicant: Radius Health, Inc. , 3M Innovative Properties Company
Inventor： Gary Hattersley , Alan Harris , Jamal Saeh , Ehab Hamed , Kenneth Brown , Daniel Dohmeier , Joan Moseman , Ying Zhang , Lisa Dick
Abstract: Disclosed are abaloparatide formulations for transdermal delivery of a therapeutically effective amount of abaloparatide, as well as transdermal patches prepared using these formulations, methods of preparing the disclosed formulations and patches, and methods of using these formulations and patches to treat osteoporosis, osteopenia, osteoarthritis, and/or bone fracture, improve bone mineral density (BMD), improve trabecular bone score (TBS), and treat, prevent, and/or reduce bone fractures.
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公开(公告)号：US20190290738A1
公开(公告)日：2019-09-26
申请号：US16279770
申请日：2019-02-19
Applicant: Radius Health, Inc. , 3M Innovative Properties Company, a wholly owned subsidiary of 3M Company
Inventor： Gary Hattersley , Kris J. Hansen , Amy S. Determan , Ying Zhang
Abstract: The present invention provides compositions, devices, methods and processes related to the intradermal delivery of PTHrP and PTHrP analogues, particularly [Glu22,25, Leu23,28,31, Aib29, Lys26,30]hPTHrP(1-34)NH2.
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公开(公告)号：US20140046292A1
公开(公告)日：2014-02-13
申请号：US13791170
申请日：2013-03-08
Applicant: Radius Health, Inc. , 3M Innovative Properties Company, a wholly owned subsidiary of 3M Company
Inventor： Gary Hattersley , Kris J. Hansen , Amy S. Determan , Ying Zhang
Abstract: The present invention provides compositions, devices, methods and processes related to the intradermal delivery of PTHrP and PTHrP analogues, particularly [Glu22,25, Leu23,28,31, Aib29, Lys26,30]hPTHrP(1-34)NH2.
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