公开(公告)号：US20200038546A1

公开(公告)日：2020-02-06

申请号：US16338803

申请日：2017-10-04

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： JAMES P. DIZIO ,  ZHICHENG TIAN ,  JASON W. BJORK ,  AMY S. DETERMAN ,  ROBERT A. ASMUS ,  JONATHAN J. O'HARE

IPC: A61L26/00

Abstract: Provided is a method of forming a fibrinogen hydrogel composition, the method including providing a fibrinogen hydrogel or precursor thereof, comprising fibrinogen hydrogel forming salt. The fibrinogen hydrogel forming salt concentration is greater than or equal to the threshold concentration to form a fibrinogen hydrogel. The method further includes denaturing the fibrinogen hydrogel such as by heating. The method optionally further includes combining the fibrinogen hydrogel with a carrier material. When present, the concentration of the carrier material typically ranges from 0.1 to about 50 wt.-%. The method further includes reducing the salt concentration below the threshold concentration to form a fibrinogen hydrogel.

公开(公告)号：US20210324150A1

公开(公告)日：2021-10-21

申请号：US16338776

申请日：2017-10-04

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jason W. Bjork ,  AMY S. DETERMAN ,  JONATHAN J. O'HARE ,  ROBERT A. ASMUS ,  JAMES P. DIZIO ,  ZHICHENG TIAN

IPC: C08J3/075 ,  C08L89/00

Abstract: The invention includes a forced-air blanket for providing a profusion of air to a patient, comprising a bottom layer with a plurality of openings configured to allow a profusion of air to pass through the bottom layer and an upper layer bonded to the bottom layer around a periphery, wherein the upper layer is also bonded to bottom layer by a plurality of linear seals and a plurality of staked seals. In an embodiment, at least one of more of the linear seals have one end which is joined to a portion of the periphery. In another embodiment, the forced-air blanket may further include at least one elongated seal that is positioned proximate to the inlet. The arrangement of the plurality of staked seals, elongated seals and linear seals assists in providing a blanket that is of a low-profile with even air distribution.

公开(公告)号：US20210100929A1

公开(公告)日：2021-04-08

申请号：US17101005

申请日：2020-11-23

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： JAMES P. DIZIO ,  ZHICHENG TIAN ,  JAMES W. BJORK ,  AMY S. DETERMAN ,  ROBERT A. ASMUS ,  JONATHAN J. O'HARE

IPC: A61L26/00

Abstract: Disclosed is a fibrinogen composition. The fibrinogen composition comprises denatured fibrinogen hydrogel having a fibrinogen concentration ranging from 0.1 to 15 wt.-% and a fibrinogen hydrogel forming salt at a concentration less than a threshold concentration to form the fibrinogen hydrogel. In some examples, the fibrinogen composition is dehydrated denatured fibrinogen hydrogel, where the fibrinogen composition comprises salt at a concentration no greater than 20 wt.-%.