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公开(公告)号：US20200038546A1
公开(公告)日：2020-02-06
申请号：US16338803
申请日：2017-10-04
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： JAMES P. DIZIO , ZHICHENG TIAN , JASON W. BJORK , AMY S. DETERMAN , ROBERT A. ASMUS , JONATHAN J. O'HARE
IPC: A61L26/00
Abstract: Provided is a method of forming a fibrinogen hydrogel composition, the method including providing a fibrinogen hydrogel or precursor thereof, comprising fibrinogen hydrogel forming salt. The fibrinogen hydrogel forming salt concentration is greater than or equal to the threshold concentration to form a fibrinogen hydrogel. The method further includes denaturing the fibrinogen hydrogel such as by heating. The method optionally further includes combining the fibrinogen hydrogel with a carrier material. When present, the concentration of the carrier material typically ranges from 0.1 to about 50 wt.-%. The method further includes reducing the salt concentration below the threshold concentration to form a fibrinogen hydrogel.
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公开(公告)号：US20180094291A1
公开(公告)日：2018-04-05
申请号：US15569552
申请日：2016-04-26
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： JASON W. BJORK , EVAN D. BRUTINEL , ADAM J. STANENAS
CPC classification number: C12Q1/06 , C12M23/04 , C12M23/20 , C12M23/34 , C12M25/06 , C12M41/34 , C12M41/36
Abstract: The present disclosure provides a culture device for enumerating colonies of microorganisms. The device can comprise a base, a coversheet, and a nonporous spacer member disposed therebetween. The spacer member comprises an aperture that defines a growth compartment. At least one adhesive layer adhered to the base or the coversheet in the growth compartment. A cold water-soluble gelling agent and a dry oxygen-scavenging reagent are adhered to the at least one adhesive layer. The oxygen-scavenging reagent consists essentially of particles having a diameter of less than 106 microns.
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公开(公告)号：US20160340709A1
公开(公告)日：2016-11-24
申请号：US15226096
申请日：2016-08-02
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： STEPHEN B. ROSCOE , SHIH-HUNG CHOU , STEPHANIE J. MOELLER , JESSE D. MILLER , KURT J. HALVERSON , JASON W. BJORK
IPC: C12Q1/04 , C07H17/075 , C07D409/04 , C07D311/16 , C07D405/04
CPC classification number: C12Q1/04 , C07D311/16 , C07D405/04 , C07D409/04 , C07H17/075 , C09B57/02 , C12Q1/045 , G01N33/525 , G01N33/582
Abstract: Compounds are provided that are either fluorogenic or fluorophoric. Compositions and articles that include the compounds are also provided. Additionally, methods of detecting a microorganism using the compounds are provided. The compounds are fluorinated and can be used advantageously under acidic conditions.
Abstract translation: 提供了荧光或荧光的化合物。 还提供了包含化合物的组合物和制品。 另外，提供使用该化合物检测微生物的方法。 化合物是氟化的，并且可以在酸性条件下有利地使用。
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公开(公告)号：US20190194595A1
公开(公告)日：2019-06-27
申请号：US16288712
申请日：2019-02-28
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： JASON W. BJORK , MARA S. CELT , ADAM J. STANENAS
CPC classification number: C12M41/36 , C12M23/20 , C12Q1/04 , C12Q1/045 , C12Q1/26 , G01N2333/90225 , G01N2333/90235
Abstract: A self-contained anaerobic environment-generating culture device is provided. The culture device includes a first substrate having opposing inner and outer surfaces, a second substrate having opposing inner and outer surfaces, a growth region disposed between the inner surfaces of the first and second substrates, an effective amount of a substantially dry enzyme component of an enzyme-mediated oxygen depletion system, an effective amount of a substantially dry enzyme substrate component of the enzyme-mediated oxygen depletion system, and a dry, cold-water-soluble gelling agent disposed in the growth region. The enzyme and enzyme substrate components are disposed in coatings in the growth region. The first and second substrates are substantially nontransmissible to gaseous oxygen. Methods of making and using the culture device area also provided.
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公开(公告)号：US20180298322A1
公开(公告)日：2018-10-18
申请号：US15569451
申请日：2016-04-26
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： JASON W. BJORK , EVAN D. BRUTINEL , ADAM J. STANENAS
Abstract: The present disclosure provides a culture device for enumerating colonies of microorganisms. The device can comprise a base, a coversheet, and a nonporous spacer member disposed therebetween. The spacer member comprises an aperture that defines a growth compartment. At least one adhesive layer is adhered to the base or the coversheet in the growth compartment. A cold water-soluble gelling agent and an effective amount of a dry carbon dioxide-generating reagent are adhered to the at least one adhesive layer. The carbon dioxide-generating reagent consists essentially of particles having a diameter of less than 106 microns.
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Patent Agency Ranking
公开(公告)号：US20180312895A1
公开(公告)日：2018-11-01
申请号：US15569579
申请日：2016-04-26
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： JASON W. BJORK , EVAN D. BRUTINEL , ADAM J. STANENAS
Abstract: The present disclosure provides a culture device for enumerating colonies of microorganisms. The device can comprise a base, a coversheet, and a nonporous spacer member disposed therebetween. The spacer member comprises an aperture that defines a growth compartment. Disposed in the growth compartment are a cold water-soluble gelling agent, a dry oxygen-scavenging reagent, a dry buffer system, and an effective amount of a dry carbon dioxide-generating reagent. The buffer system is selected such that, when the growth compartment is hydrated with a predetermined volume of deionized water, an aqueous mixture with a pH less than or equal to 6.35 is formed.
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公开(公告)号：US20170233691A1
公开(公告)日：2017-08-17
申请号：US15503481
申请日：2015-08-19
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： EVAN D. BRUTINEL , JASON W. BJORK , ADAM J. STANENAS
Abstract: The present disclosure provides a culture device for enumerating colonies of sulfate-reducing microorganisms. The device includes a body having a waterproof base, a waterproof coversheet attached to the base, and a growth compartment disposed therebetween. The growth compartment has a perimeter and an opening. A portion of the perimeter is defined by a waterproof seal. The portion can include >50% of the perimeter. Disposed in the growth compartment are a dry cold water-soluble gelling agent, a dry culture medium selected to facilitate growth of a sulfate-reducing bacterium or indicator reagent for detecting hydrogen sulfide production by a sulfate-reducing bacterium, and a dry first oxygen-scavenging reagent.
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公开(公告)号：US20170191108A1
公开(公告)日：2017-07-06
申请号：US15308622
申请日：2015-05-13
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： JASON W. BJORK , ADAM J. STANENAS , WENSHENG XIA
Abstract: A culture system for culturing a microaerophilic or an anaerobic microorganism is provided. The culture system can include effective amounts of i) an enzyme of an oxidoreductase family and ii) a substrate for said enzyme, a container, and a predetermined volume of aqueous medium that supports growth of said anaerobic or microaerophilic microorganism. The enzyme can be selected from a group consisting of ascorbic acid oxidase and laccase. The effective amounts are effective to deplete dissolved oxygen in the predetermined volume to a concentration that facilitates growth of a microaerophilic microorganism or an obligately-anaerobic microorganism. A method of using the system is also provided.
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公开(公告)号：US20160138070A1
公开(公告)日：2016-05-19
申请号：US15002696
申请日：2016-01-21
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： WENSHENG XIA , PATRICK A. MACH , JOSEPH M. BEAURLINE , JASON W. BJORK , JIE J. LIU
Abstract: A latent effervescent body comprising a selective agent is disclosed. A method of using the latent effervescent body in a method to selectively enrich a target microorganism is also disclosed. The method comprises providing a sample, a culture medium, and the latent effervescent body. The method further comprises contacting the sample, the culture medium, and the latent effervescent body under conditions to facilitate growth of the target microorganism. The method further comprises releasing the selective agent from the latent effervescent body. Optionally, the method includes detecting a microorganism.
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公开(公告)号：US20150010941A1
公开(公告)日：2015-01-08
申请号：US14493991
申请日：2014-09-23
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： ROBERT F. YOUNG , PATRICK A. MACH , MICHAEL E. HUGHES , CHRISTINE A. BINSFELD , JASON W. BJORK , MARA S. CELT , HENRY J. LUBRANT
IPC: C12Q1/04
Abstract: The disclosure provides culture devices and methods useful for detecting acid-producing bacteria in a sample. The devices include a nutrient medium and a pH indicator to detect and differentiate acid-producing microorganisms, such as lactic acid bacteria. Methods of use include detecting or enumerating acid-producing microorganisms. The methods further provide for the detection of gas-producing acid-producing bacteria.
Abstract translation: 本公开提供了用于检测样品中产酸细菌的培养装置和方法。 该装置包括营养培养基和pH指示剂以检测和分解产酸微生物如乳酸菌。 使用方法包括检测或列举产酸微生物。 该方法进一步提供产气产酸细菌的检测。
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