公开(公告)号：US09994912B2

公开(公告)日：2018-06-12

申请号：US14788195

申请日：2015-06-30

申请人： ABBOTT MOLECULAR INC.

发明人： Ying Zhang ,  Ekaterina Pestova ,  Jing Du ,  Ping Liu ,  Tracey Colpitts

IPC分类号： C12Q1/6886 ,  C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/156

摘要： Methods of distinguishing and identifying a patient with aggressive/indolent, prostatic adenocarcinoma comprising contacting a sample from the patient with a set of detectably labeled probes under hybridization conditions and determining the presence of chromosomal abnormalities in the sample; sets of probes for use in such methods; and kits comprising a set of probes and instructions for distinguishing or identifying a patient as having aggressive/indolent, prostatic adenocarcinoma.

公开(公告)号：US20180291466A1

公开(公告)日：2018-10-11

申请号：US16005228

申请日：2018-06-11

申请人： ABBOTT MOLECULAR INC.

发明人： Ying Zhang ,  Ekaterina Pestova ,  Jing Du ,  Ping Liu ,  Tracey Colpitts

IPC分类号： C12Q1/6886

摘要： Methods of distinguishing and identifying a patient with aggressive/indolent, prostatic adenocarcinoma comprising contacting a sample from the patient with a set of detectably labeled probes under hybridization conditions and determining the presence of chromosomal abnormalities in the sample; sets of probes for use in such methods; and kits comprising a set of probes and instructions for distinguishing or identifying a patient as having aggressive/indolent, prostatic adenocarcinoma.

公开(公告)号：US10604812B2

公开(公告)日：2020-03-31

申请号：US16005228

申请日：2018-06-11

申请人： ABBOTT MOLECULAR INC.

发明人： Ying Zhang ,  Ekaterina Pestova ,  Jing Du ,  Ping Liu ,  Tracey Colpitts

IPC分类号： C12Q1/6886

摘要： Methods of distinguishing and identifying a patient with aggressive/indolent, prostatic adenocarcinoma comprising contacting a sample from the patient with a set of detectably labeled probes under hybridization conditions and determining the presence of chromosomal abnormalities in the sample; sets of probes for use in such methods; and kits comprising a set of probes and instructions for distinguishing or identifying a patient as having aggressive/indolent, prostatic adenocarcinoma.

公开(公告)号：US20160320393A1

公开(公告)日：2016-11-03

申请号：US15151465

申请日：2016-05-10

申请人： ABBOTT MOLECULAR INC.

发明人： Tracey Colpitts ,  Eric L. Russell ,  Stephen Frost ,  Javier Ramirez ,  Bhawani Singh ,  John C. Russell

IPC分类号： G01N33/574

CPC分类号： G01N33/57423 ,  C07K14/4738 ,  G01N2333/47 ,  G01N2333/4703 ,  G01N2333/4725 ,  G01N2333/4739 ,  G01N2333/4742 ,  G01N2333/4748 ,  G01N2333/705 ,  G01N2333/70596 ,  G01N2333/775 ,  G01N2333/8125 ,  G01N2333/91205

摘要： The present invention relates to rapid, sensitive methods for determining whether a subject is at risk of developing lung cancer or has lung cancer based on certain combinations or biomarkers or biomarkers and biometric parameters.

摘要翻译： 本发明涉及用于确定受试者是否处于基于某些组合或生物标志物或生物标志物和生物测定参数发展为肺癌或具有肺癌的风险的快速，敏感的方法。

公开(公告)号：US20160002735A1

公开(公告)日：2016-01-07

申请号：US14788195

申请日：2015-06-30

申请人： ABBOTT MOLECULAR INC.

发明人： Ying Zhang ,  Ekaterina Pestova ,  Jing Du ,  Ping Liu ,  Tracey Colpitts

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/156

摘要： Methods of distinguishing and identifying a patient with aggressive/indolent, prostatic adenocarcinoma comprising contacting a sample from the patient with a set of detectably labeled probes under hybridization conditions and determining the presence of chromosomal abnormalities in the sample; sets of probes for use in such methods; and kits comprising a set of probes and instructions for distinguishing or identifying a patient as having aggressive/indolent, prostatic adenocarcinoma.

摘要翻译： 区分和鉴定具有侵袭性/惰性前列腺腺癌的患者的方法，包括在杂交条件下将来自患者的样品与一组可检测标记的探针接触并确定样品中染色体异常的存在; 用于这种方法的探针组; 以及包含一组探针和用于区分或鉴别患者具有侵袭性/惰性前列腺腺癌的试剂盒。