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公开(公告)号:US20250032631A1
公开(公告)日:2025-01-30
申请号:US18915981
申请日:2024-10-15
Applicant: AbbVie Inc.
Inventor: Emily Jean Faivre , Andrew C. Phillips , Regina M. Reilly , Eoghainin O'Hainmhire
Abstract: The present disclosure provides SEZ6 antibody drug conjugates (ADCs), including compositions and methods of using such ADCs.
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公开(公告)号:US20240199745A1
公开(公告)日:2024-06-20
申请号:US18349904
申请日:2023-07-10
Applicant: AbbVie Inc.
Inventor: Erwin R. Boghaert , Milan Bruncko , George Doherty , Robin R. Frey , Andrew S. Judd , Andrew C. Phillips , Xiaohong Song , Andrew J. Souers , Gerard M. Sullivan , Zhi-Fu Tao
CPC classification number: C07K16/2863 , A61K47/65 , A61K47/6803 , A61K47/6845 , A61K47/6849 , A61K47/6855 , A61K47/6857 , A61K47/6889 , A61P35/00 , A61K2039/505 , A61K2039/545 , A61K45/06 , C07K16/22 , C07K16/2827
Abstract: The invention relates to anti-Epidermal Growth Factor Receptor (EGFR) antibody drug conjugates (ADCs) which inhibit Bcl-xL, including compositions and methods of using said ADCs.
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公开(公告)号:US20170072065A1
公开(公告)日:2017-03-16
申请号:US15349692
申请日:2016-11-11
Applicant: AbbVie Inc.
Inventor: Edward B. Reilly , Andrew C. Phillips , Lorenzo Benatuil , Fritz G. Buchanan , Jonathan A. Meulbroek , Chung-Ming Hsieh , Jennifer Perez
CPC classification number: A61K47/6811 , A61K47/6803 , A61K47/6847 , A61K47/6849 , A61K47/6851 , A61K47/6857 , A61K47/6863 , A61K47/6865 , A61K47/6889 , A61K2039/505 , C07K14/00 , C07K16/2863 , C07K16/30 , C07K16/3023 , C07K16/3046 , C07K16/3053 , C07K2317/21 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The invention relates to anti-epidermal growth factor (EGFR) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
Abstract translation: 本发明涉及抗表皮生长因子(EGFR)抗体和抗体药物偶联物(ADC),包括使用所述抗体和ADC的组合物和方法。
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公开(公告)号:US20210171637A1
公开(公告)日:2021-06-10
申请号:US16819036
申请日:2020-03-13
Applicant: AbbVie Inc.
Inventor: Lorenzo Benatuil , Debra Chao , Kamel Izeradjene , Andrew S. Judd , Andrew C. Phillips , Andrew J. Souers , Archana Thakur , Milan Bruncko
IPC: C07K16/28 , A61K47/68 , A61K31/498 , A61K31/437 , A61K31/519
Abstract: The invention relates to B7 homology 3 protein (B7-H3) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
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公开(公告)号:US20200002421A1
公开(公告)日:2020-01-02
申请号:US16308622
申请日:2017-06-07
Applicant: AbbVie Inc.
Inventor: Lorenzo Benatuil , Milan Bruncko , Debra Chao , Kamel Izeradjene , Andrew S. Judd , Andrew C. Phillips , Andrew J. Souers , Archana Thakur , George Doherty , Robin R. Frey , Xiaohong Song , Gerard M. Sullivan , Zhi-Fu Tao
Abstract: The invention relates to B7 homology 3 protein (B7-H3) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
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公开(公告)号:US20190134216A1
公开(公告)日:2019-05-09
申请号:US16154229
申请日:2018-10-08
Applicant: AbbVie Inc.
Inventor: Edward B. Reilly , Andrew C. Phillips , Lorenzo Benatuil , Chung-Ming Hsieh , Jennifer Perez
Abstract: The invention relates to anti-epidermal growth factor (EGFR) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
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公开(公告)号:US20150337042A1
公开(公告)日:2015-11-26
申请号:US14664453
申请日:2015-03-20
Applicant: ABBVIE INC.
Inventor: Edward B. Reilly , Andrew C. Phillips , Lorenzo Benatuil , Fritz G. Buchanan , Jonathan A. Meulbroek , Chung-Ming Hsieh , Jennifer Perez
CPC classification number: A61K47/6811 , A61K47/6803 , A61K47/6847 , A61K47/6849 , A61K47/6851 , A61K47/6857 , A61K47/6863 , A61K47/6865 , A61K47/6889 , A61K2039/505 , C07K14/00 , C07K16/2863 , C07K16/30 , C07K16/3023 , C07K16/3046 , C07K16/3053 , C07K2317/21 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The invention relates to anti-epidermal growth factor (EGFR) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
Abstract translation: 本发明涉及抗表皮生长因子(EGFR)抗体和抗体药物偶联物(ADC),包括使用所述抗体和ADC的组合物和方法。
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公开(公告)号:US20250163159A1
公开(公告)日:2025-05-22
申请号:US18670261
申请日:2024-05-21
Applicant: AbbVie Inc.
Inventor: Edward B. Reilly , Andrew C. Phillips , Lorenzo Benatuil , Chung-Ming Hsieh , Jennifer Perez
Abstract: The invention relates to anti-epidermal growth factor (EGFR) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
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公开(公告)号:US20230077680A1
公开(公告)日:2023-03-16
申请号:US17447362
申请日:2021-09-10
Applicant: AbbVie Inc.
Inventor: Erwin R. Boghaert , Milan Bruncko , Andrew S. Judd , Andrew C. Phillips , Andrew J. Souers
Abstract: The invention relates to anti-Epidermal Growth Factor Receptor (EGFR) antibody drug conjugates (ADCs) which inhibit Bcl-xL, including compositions and methods of using said ADCs.
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公开(公告)号:US20200002432A1
公开(公告)日:2020-01-02
申请号:US16308755
申请日:2017-06-08
Applicant: AbbVie Inc.
Inventor: Lorenzo Benatuil , Milan Bruncko , George Doherty , Robin R. Frey , Andrew S. Judd , Yingchun Li , Andrew Mccluskey , Andrew C. Phillips , Darren C. Phillips , Jane Seagal , Xiaohong Song , Andrew J. Souers , Gerard M. Sullivan , Zhi-Fu Tao
Abstract: The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
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