公开(公告)号：US20240270829A1

公开(公告)日：2024-08-15

申请号：US18395150

申请日：2023-12-22

申请人： AC Immune SA

发明人： Andrea Pfeifer ,  Andreas Muhs ,  Rime Madani ,  Pavel Vasilyevich Belichenko ,  William Charles Mobley

IPC分类号： C07K16/18 ,  A61K39/00

CPC分类号： C07K16/18 ,  A61K39/0007 ,  A61K2039/55555 ,  A61K2039/6018

摘要： The present invention provides means for treating, alleviating and preventing amyloid-related pathology in young to middle-aged subjects with Down's syndrome (DS). In particular, the present invention provides antigenic peptide fragments derived from amyloid protein or amyloid-like protein for use in the preventive treatment of amyloid-related pathology in young to middle-aged subjects with Down's syndrome.