公开(公告)号：US10086054B2

公开(公告)日：2018-10-02

申请号：US14392341

申请日：2014-06-26

Applicant: ACADEMIA SINICA

Inventor： Chi-Huey Wong ,  Chung-Yi Wu ,  Hong-Yang Chuang ,  Chien-Tai Ren

IPC: C07H15/04 ,  A61K39/00 ,  A61K39/385 ,  A61K31/7028 ,  C07K14/47 ,  A61K49/00 ,  C07H15/10 ,  C07H15/14

Abstract: Described herein are synthetic glycan conjugates, immunogenic compositions thereof, vaccines thereof, and kits thereof. The present invention further provides methods of using the synthetic glycan conjugates, immunogenic compositions, or vaccines thereof to treat and/or prevent and/or diagnose proliferative diseases such as cancer. The provided glycan conjugate comprises a carrier and a glycan moiety of Formula (I-i) or Formula (I-ii): (structurally represented).