公开(公告)号：US11517600B2

公开(公告)日：2022-12-06

申请号：US16963992

申请日：2018-05-29

Applicant: ACADEMIA SINICA

Inventor： Lie-Fen Shyur ,  Maria Karmella Apaya ,  Meng-Ting Chang

IPC: A61P35/04 ,  A61K36/28 ,  A61K31/045 ,  A61K31/7032 ,  A61K31/704

Abstract: A method for treating breast cancer and/or treating breast cancer metastasis in a subject in need of such treatment including administering to said subject an effective amount of Crassocephalum rabens extract and optionally a pharmaceutically acceptable carrier or excipient.

公开(公告)号：US10434132B2

公开(公告)日：2019-10-08

申请号：US16172428

申请日：2018-10-26

Applicant: ACADEMIA SINICA

Inventor： Lie-Fen Shyur ,  Jia-Hua Feng ,  Maria Karmella Apaya

IPC: A61K36/00 ,  A61K36/88 ,  A61K31/25 ,  A61K36/28 ,  A61K8/9794 ,  A61Q19/02 ,  A61P1/16 ,  A61P31/04

Abstract: The present invention is related to a galactolipids-enriched plant extract, prepared by extracting a plant sample selected from a group consisting of: Gynura divaricata subsp. formosana (Asteraceae) (GD), Murdannia bracteata (C. B. Clarke) J. K. Morton ex D. Y. Hong (Commelinaceae) (MB), and Crassocephalum rabens S. Moore (Asteraceae) (CR) with a series of solvents. A pharmaceutical, nutritional, or healthcare composition for protecting or treating acute fulminant hepatitis, for protecting or treating sepsis or related indication thereof, and a composition for skin whitening are also provided herein. These compositions all comprise effective amounts of the galactolipids-enriched plant extracts or purified compounds thereof as bioactive ingredients.