-
公开(公告)号:US20160153013A1
公开(公告)日:2016-06-02
申请号:US14945046
申请日:2015-11-18
发明人: Thomas WALTHER , Helene CORDIER , Christopher TOPHAM , Isabelle ANDRE , Magali REMAUD-SIMEON , Robert HUET , Jean-Marie FRANCOIS
CPC分类号: C12P7/42 , C07F9/096 , C12N9/0006 , C12N9/0008 , C12N9/1217 , C12N15/70 , C12P7/40 , C12P9/00 , C12Y101/01 , C12Y102/01011 , C12Y102/01018 , C12Y207/02004
摘要: A method of producing 2,4-dihydroxybutyric acid (2,4-DHB) by a synthetic pathway that includes transforming malate into 4-phospho-malate using a malate kinase, then transforming 4-phospho-malate into malate-4-semialdehyde using a malate semialdehyde dehydrogenase, and then transforming malate-4-semialdehyde into 2,4-DHB using a DHB dehydrogenase.
摘要翻译: 一种通过合成途径生产2,4-二羟基丁酸(2,4-DHB)的方法,其包括使用苹果酸激酶将苹果酸转化为4-磷酸苹果酸,然后将4-磷酸苹果酸转化为苹果酸4-半醛,使用 苹果酸半醛脱氢酶,然后使用DHB脱氢酶将苹果酸4-半醛醛转化为2,4-DHB。