公开(公告)号：US20180250403A1

公开(公告)日：2018-09-06

申请号：US15754573

申请日：2016-08-24

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Paul Lorenz BIGLIARDI ,  Mei BIGLIARDI-QI ,  Bhimsen ROUT ,  Brendan BURKETT ,  Aakanksha PANT

IPC: A61K41/00 ,  A61K47/10 ,  A61K47/18 ,  A61P35/00

CPC classification number: A61K41/0038 ,  A61K8/64 ,  A61K9/0014 ,  A61K38/08 ,  A61K41/0057 ,  A61K47/10 ,  A61K47/18 ,  A61K47/64 ,  A61P35/00 ,  A61Q19/02 ,  G01N33/5743 ,  G01N33/57484

Abstract: The present invention relates to improved compositions for photodynamic therapy (PDT) for the selective destruction of malignant, diseased, or infected cells or infective agents without causing damage to normal cells. In an embodiment, the composition comprises a photosensitising agent coupled to a ligand, wherein the ligand selectively binds to a targeted receptor and comprises an isolated peptide molecule having less than 10 or 8 amino acids.