公开(公告)号：US09694127B2

公开(公告)日：2017-07-04

申请号：US14395810

申请日：2013-04-22

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Daniele Zink ,  Yar Oo Zay

IPC: A61M1/34 ,  B01D63/02

CPC classification number: A61M1/3489 ,  A61M1/3417 ,  A61M1/3434 ,  A61M1/3472 ,  B01D63/02

Abstract: There is provided a bioreactor device having cells, including human primary proximal tubule cells (HPTCs) or HPTC-like cells on the exterior surface of hollow fiber membranes included within the device. Also provided are bioartificial kidney devices incorporate the bioreactor device and methods of using such devices.

公开(公告)号：US20150076066A1

公开(公告)日：2015-03-19

申请号：US14395810

申请日：2013-04-22

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Daniele Zink ,  Yar Oo Zay

IPC: A61M1/34 ,  B01D63/02

CPC classification number: A61M1/3489 ,  A61M1/3417 ,  A61M1/3434 ,  A61M1/3472 ,  B01D63/02

Abstract: There is provided a bioreactor device having cells, including human primary proximal tubule cells (HPTCs) or HPTC-like cells on the exterior surface of hollow fiber membranes included within the device. Also provided are bioartificial kidney devices incorporate the bioreactor device and methods of using such devices.

Abstract translation: 提供了具有细胞的生物反应器装置，其包括在装置内的中空纤维膜的外表面上包括人类初级近端小管细胞（HPTC）或HPTC样细胞。 还提供了包括生物反应器装置的生物人造肾装置和使用这种装置的方法。