公开(公告)号：US20150110845A1

公开(公告)日：2015-04-23

申请号：US14511240

申请日：2014-10-10

Applicant: Agency for Science, Technology and Research

Inventor： Yen Nee Tan ,  Yuan Chong Jason Lim ,  Chao Wang ,  Lian Hui Zhang

IPC: A61K33/38 ,  A01N59/16 ,  A61K9/00 ,  A61K31/7088 ,  A61K31/713 ,  A61K9/14 ,  A01N43/90 ,  A01N25/26

CPC classification number: A61K9/0014 ,  A01N59/16 ,  A61K9/5153 ,  A61K31/7088 ,  A61K31/713 ,  A61K31/7135 ,  B82Y5/00 ,  A01N43/90

Abstract: There is provided a polynucleotide-templated metal nanocluster for use in therapy. There is also provided use of a polynucleotide-templated metal nanocluster in the manufacture of a medicament for prophylactically or therapeutically treating a microbial infection as well as a method of prophylactically or therapeutically treating a microbial infection comprising administering to a subject a polynucleotide-templated metal nanocluster. There is also provided an antimicrobial agent comprising a polynucleotide-templated metal nanocluster.

Abstract translation: 提供了用于治疗的多核苷酸模板化金属纳米团簇。 还提供了多核苷酸模板化的金属纳米簇在制备用于预防或治疗微生物感染的药物中的用途以及预防或治疗性治疗微生物感染的方法，包括向受试者施用多核苷酸模板化的金属纳米簇 。 还提供了包含多核苷酸模板化的金属纳米簇的抗微生物剂。

公开(公告)号：US20240352208A1

公开(公告)日：2024-10-24

申请号：US18687421

申请日：2022-08-25

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Simin Shermin Goh ,  Yuan Chong Jason Lim ,  Kim Kui Georgina Estelle Seah ,  Yan Xuan Angeline Tan ,  Chuan Hui Lionel Moh

IPC: C08J5/22

CPC classification number: C08J5/2243 ,  C08J2367/07

Abstract: There is provided an ion selective membrane comprising a polymer matrix and an ionic lipophilic additive covalently bonded to the polymer matrix. There are also provided a method of preparing the ion selective membrane, an ion selective electrode comprising the ion selective membrane and a method of preparing the ion selective electrode.