公开(公告)号：US20230126290A1

公开(公告)日：2023-04-27

申请号：US17946750

申请日：2022-09-16

Applicant: AGILENT TECHNOLOGIES, INC.

Inventor： Ruwan T. KURULUGAMA ,  Kenneth R. NEWTON

IPC: H01J49/14 ,  H01J49/04 ,  H01J49/40

Abstract: An ion source may include an ionization chamber to be maintained at atmospheric-pressure. The ion source may further include a reduced-pressure chamber to be maintained at sub-atmospheric pressure, and an ion transfer device comprising an inlet in the ionization chamber and an outlet in the reduced-pressure chamber. The ion transfer device may define an ion path from the inlet to the outlet. The ion transfer device may be positioned to emit ions and neutral gas molecules from the outlet as an expanding beam comprising a low-gas density zone enveloped by a high-gas density region that includes a gas density that is higher than the low-gas density zone. The ion source may be utilized, for example, for ion mobility spectrometry (IMS), mass spectrometry (MS), and hybrid IM-MS.