专利检索 ap:("AGV Discovery ENSCM" OR "Institut National de la Sante et de la Recherche Medicale (INSERM)" OR "Centre National de la Recherche Scientifique (CNRS)" OR "Universite de Montpellier") AND inv:"Cédric Bories" 第 1 页

1.

发明授权
Zaindole derivatives and their use as ERK kinase inhibitors 有权

公开(公告)号：US10995089B2

公开(公告)日：2021-05-04

申请号：US15777386

申请日：2016-11-17

申请人： AGV Discovery ENSCM , Institut National de la Sante et de la Recherche Medicale (INSERM) , Centre National de la Recherche Scientifique (CNRS) , Universite de Montpellier

发明人： Jean-François Guichou , Cédric Bories , Clément Geoffroy , Charline Duquenne , Muriel Gelin , Gilles Labesse , Yannick Bessin , Loic Mathieu

IPC分类号： C07D471/04 , A61P35/00 , C07D519/00 , C07F9/6561 , C07D491/048 , C07D491/107 , C07D491/113

摘要： The present invention concerns a compound of formula (I): H or one of its pharmaceutically acceptable salts, especially for use as inhibitors of the ERK kinase activity in particular ERK2 activity, it also concerns prodrugs of these compounds.

2.

发明授权
Azaindole derivatives and their use as ERK kinase inhibitors 有权

公开(公告)号：US11708364B2

公开(公告)日：2023-07-25

申请号：US17216114

申请日：2021-03-29

申请人： AGV Discovery , Institut National de la Sante et de la Recherche Medicale (INSERM) , Centre National de la Recherche Scientifique (CNRS) , Universite De Montpellier

发明人： Jean-François Guichou , Cédric Bories , Clément Geoffroy , Charline Duquenne , Muriel Gelin , Gilles Labesse , Yannick Bessin , Loic Mathieu

IPC分类号： A61K31/4353 , C07D471/04 , A61P35/00 , C07D519/00 , C07F9/6561 , C07D491/048 , C07D491/113 , C07D491/107

CPC分类号： C07D471/04 , A61K31/4353 , A61P35/00 , C07D491/048 , C07D491/107 , C07D491/113 , C07D519/00 , C07F9/6561

摘要： The present invention concerns a compound of formula (I), or one of its pharmaceutically acceptable salts, especially for use as inhibitors of the ERK kinase activity in particular ERK2 activity, it also concerns prodrugs of these compounds.

3.

发明授权
Azaindole derivatives and their use as ERK kinase inhibitors 有权

公开(公告)号：US11827637B2

公开(公告)日：2023-11-28

申请号：US18096996

申请日：2023-01-13

申请人： AGV Discovery , Institut National de la Sante et de la Recherche Medicale (INSERM) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) , Universite De Montpellier

发明人： Cédric Bories , Loïc Mathieu , Jean-François Guichou , Muriel Gelin , Aurélien Biechy

IPC分类号： C07D413/14 , A61K31/5377 , C07D471/04 , C07D213/643 , C07F5/02

CPC分类号： C07D471/04 , C07D213/643 , C07F5/027

摘要： The present invention concerns a compound of formula (I):

or one of its pharmaceutically acceptable salts, especially for use as inhibitors of the ERK kinase activity, in particular ERK2 activity.