公开(公告)号：US20250101129A1

公开(公告)日：2025-03-27

申请号：US18966063

申请日：2024-12-02

Applicant: Ajinomoto Co., Inc.

Inventor： Yutaka MATSUDA ,  Tomohiro FUJII ,  Kenichiro ITO ,  Kazutoshi TAKAHASHI ,  Yoshihiko MATSUDA ,  Hiroki YAMAGUCHI ,  Naoko TSUYOSHI ,  Hayato NAGANO ,  Rika TAKASUGI

IPC: C07K16/32 ,  C07K16/28

Abstract: The present invention relates to a technology for easy chemical modification of only one heavy chain in the constituent unit of an antibody (immunoglobulin unit containing two heavy chains and optionally two light chains). More particularly, the present invention relates to a compound or a salt thereof, containing (A) an affinity substance containing first and second affinity moieties each having an affinity to the constant region in a heavy chain of an antibody; and (B) a reactive group for the antibody.

公开(公告)号：US20250026799A1

公开(公告)日：2025-01-23

申请号：US18914383

申请日：2024-10-14

Applicant: AJINOMOTO CO., INC.

Inventor： Naoko TSUYOSHI ,  Teruhisa MANNEN ,  Yoshihiko MATSUDA ,  Shimpei OGAWA ,  Yasumichi KOSEKI ,  Tomomi KADO

IPC: C07K14/50 ,  C12N5/077

Abstract: A method of producing cultured meat is provided. Cultured meat is produced by culturing animal cells in the presence of bovine basic fibroblast growth factor (bbFGF) produced by using a coryneform bacterium as an expression host.