公开(公告)号：US20150011511A1

公开(公告)日：2015-01-08

申请号：US14496363

申请日：2014-09-25

Applicant: AJINOMOTO CO., INC.

Inventor： Atsushi KONISHI ,  Munetaka TOKUMASU ,  Tamotsu SUZUKI ,  Takahiro KOSHIBA ,  Koji OHSUMI ,  OSAMU IKEHARA ,  Yuko KODAMA

IPC: C07D307/68 ,  C07D405/06 ,  C07F9/38 ,  C07C53/18

CPC classification number: A61K31/4535 ,  A61K31/341 ,  A61K31/381 ,  A61K31/4025 ,  A61K31/426 ,  A61K31/4525 ,  C07C53/18 ,  C07D277/20 ,  C07D277/56 ,  C07D307/68 ,  C07D333/38 ,  C07D405/06 ,  C07F9/3808 ,  C07F9/65515

Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.

Abstract translation: 由式（I）表示的化合物：其中每个符号如说明书中所定义，及其药学上可接受的盐可用作具有丝氨酸蛋白酶抑制作用的高血糖抑制剂和用作糖尿病的预防或治疗药物。

公开(公告)号：US20150313889A1

公开(公告)日：2015-11-05

申请号：US14799130

申请日：2015-07-14

Applicant: AJINOMOTO CO., INC.

Inventor： Atsushi KONISHI ,  Munetaka TOKUMASU ,  Tamotsu SUZUKI ,  Takahiro KOSHIBA ,  Koji OHSUMI ,  Osamu IKEHARA ,  Yuko KODAMA

IPC: A61K31/4535 ,  A61K31/4525 ,  A61K31/381 ,  A61K31/426 ,  A61K31/341 ,  A61K31/4025

CPC classification number: A61K31/4535 ,  A61K31/341 ,  A61K31/381 ,  A61K31/4025 ,  A61K31/426 ,  A61K31/4525 ,  C07C53/18 ,  C07D277/20 ,  C07D277/56 ,  C07D307/68 ,  C07D333/38 ,  C07D405/06 ,  C07F9/3808 ,  C07F9/65515

Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.