公开(公告)号：US12007327B2

公开(公告)日：2024-06-11

申请号：US17173327

申请日：2021-02-11

Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Hyun C Yoon ,  Ka Ram Kim ,  Hyeong Jin Chun

IPC: C09K11/77 ,  C12Q1/06 ,  G01N21/64 ,  G02B5/12

CPC classification number: G01N21/6428 ,  C09K11/7773 ,  C12Q1/06 ,  G01N21/6402 ,  G01N21/6456 ,  G02B5/12 ,  G01N2201/06113

Abstract: An optical bio-sensing device includes a transparent substrate covering a top of a space accommodating therein a sample containing a target bio-material; a signal converter fixed to the transparent substrate, and including the upconversion nanoparticles for receiving incident light and emitting converted light of a wavelength shorter than a wavelength of the incident light; a signal reflector including retroreflection particles bindable to the signal converter via the target bio-material, wherein the retroreflection particles retroreflect the converted light; a light source for irradiating the incident light to the signal converter; and a light receiver for receiving light retroreflected from the signal reflector.