公开(公告)号：US20240009349A1

公开(公告)日：2024-01-11

申请号：US18370878

申请日：2023-09-21

Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Yun-Hoon CHOUNG ,  Jong Hoon CHUNG ,  Hoon SEONWOO ,  Kyoung-Je JANG ,  Beomyong SHIN

IPC: A61L27/18 ,  A61L27/54 ,  C08G63/08 ,  D01D5/00

CPC classification number: A61L27/18 ,  A61L27/54 ,  C08G63/08 ,  D01D5/003 ,  A61F2/18

Abstract: Disclosed is a method of treating a chronic tympanic perforation with a PCL patch tissue regeneration scaffold comprising preparing solution by adding polycaprolactone (PCL) and an acid to an organic solvent; preparing an electrospinning solution by adding a growth factor to the solution and stirring; collecting nanofibers arranged in a spindle shape on a collector by connecting the electrospinning solution prepared to a syringe pump and operating the electrospinning device; and administering the PCL patch tissue regeneration scaffold to a subject.