公开(公告)号：US20240287204A1

公开(公告)日：2024-08-29

申请号：US18392569

申请日：2023-12-21

Applicant: ALECTOR LLC

Inventor： Seung-Joo LEE ,  Spencer Liang ,  Angie YEE ,  Marina ROELL ,  Arnon ROSENTHAL

IPC: C07K16/40 ,  A61K39/00 ,  A61P35/00 ,  C07K16/28

CPC classification number: C07K16/40 ,  A61P35/00 ,  C07K16/2818 ,  C07K16/2827 ,  A61K2039/507 ,  C07K2317/56 ,  C07K2317/622 ,  C07K2317/76

Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a MerTK polypeptide, e.g., a mammalian MerTK or human MerTK, and use of such compositions in treating an individual in need thereof.

公开(公告)号：US11897968B2

公开(公告)日：2024-02-13

申请号：US17118921

申请日：2020-12-11

Applicant: Alector LLC

Inventor： Seung-Joo Lee ,  Spencer Liang ,  Angie Yee ,  Marina Roell ,  Arnon Rosenthal

IPC: C07K16/40 ,  A61K39/395 ,  A61P35/00 ,  C07K16/28 ,  A61K39/00

CPC classification number: C07K16/40 ,  A61P35/00 ,  C07K16/2818 ,  C07K16/2827 ,  A61K2039/507 ,  C07K2317/56 ,  C07K2317/622 ,  C07K2317/76

Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a MerTK polypeptide, e.g., a mammalian MerTK or human MerTK, and use of such compositions in treating an individual in need thereof.

公开(公告)号：US11987612B2

公开(公告)日：2024-05-21

申请号：US17088149

申请日：2020-11-03

Applicant: Alector LLC

Inventor： Spencer Liang ,  Samuel Nalle ,  Jeonghoon Sun ,  Hua Long ,  Rashmi Bankoti

IPC: C07K14/705 ,  A61K38/17 ,  A61K39/00 ,  A61K45/06 ,  A61P35/00 ,  A61P35/04 ,  C07K16/28

CPC classification number: C07K14/70503 ,  A61K38/1774 ,  A61K45/06 ,  A61P35/00 ,  A61P35/04 ,  C07K16/2818 ,  C07K16/2827 ,  A61K2039/545 ,  C07K2317/76 ,  C07K2319/30

Abstract: The present disclosure is generally directed to Siglec-9 ECDs and Siglec-9 ECD fusion molecules, and methods of treatment using Siglec-9 ECDs and Siglec-9 ECD fusion molecules.

公开(公告)号：US20240279305A1

公开(公告)日：2024-08-22

申请号：US18637627

申请日：2024-04-17

Applicant: Alector LLC

Inventor： Spencer Liang ,  Samuel Nalle ,  Jeonghoon Sun ,  Rashmi Bankoti ,  Hua Long

IPC: C07K14/705 ,  A61K38/17 ,  A61K39/00 ,  A61K45/06 ,  A61P35/00 ,  A61P35/04 ,  C07K16/28

CPC classification number: C07K14/70503 ,  A61K38/1774 ,  A61K45/06 ,  A61P35/00 ,  A61P35/04 ,  C07K16/2818 ,  C07K16/2827 ,  A61K2039/545 ,  C07K2317/76 ,  C07K2319/30

Abstract: The present disclosure is generally directed to Siglec-9 ECDs and Siglec-9 ECD fusion molecules, and methods of treatment using Siglec-9 ECDs and Siglec-9 ECD fusion molecules.

公开(公告)号：US20210284710A1

公开(公告)日：2021-09-16

申请号：US17088149

申请日：2020-11-03

Applicant: Alector LLC

Inventor： Spencer Liang ,  Samuel Nalle ,  Jeonghoon Sun ,  Hua Long ,  Rashmi Bankoti

IPC: C07K14/705 ,  A61P35/00 ,  A61P35/04 ,  C07K16/28 ,  A61K45/06 ,  A61K38/17

Abstract: The present disclosure is generally directed to Siglec-9 ECDs and Siglec-9 ECD fusion molecules, and methods of treatment using Siglec-9 ECDs and Siglec-9 ECD fusion molecules.