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公开(公告)号：US11208377B2
公开(公告)日：2021-12-28
申请号：US16103607
申请日：2018-08-14
申请人： ALLERGAN, INC.
发明人： Christopher D. Hein , Tien T. Duong , Santosh Sinha , Ling Li , Jeremiah H. Nguyen , David W. Old , Robert Burk , Veena Viswanath , Sandhya Rao , John E. Donello
IPC分类号： C07C311/39 , A61P17/06 , C07C237/44 , A61P27/02 , C07C211/52 , C07D307/36 , C07D307/79 , C07D215/42 , C07B59/00 , C07D333/54 , C07C311/43 , A61P29/00
摘要： Described herein are compounds, or pharmaceutically acceptable salts thereof, of the following formula: The compounds are useful for treating inflammatory and autoimmune diseases.
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公开(公告)号：US20180170858A1
公开(公告)日：2018-06-21
申请号：US15899867
申请日：2018-02-20
申请人： ALLERGAN, INC.
发明人： David W. Old , Christopher D. Hein
IPC分类号： C07C235/40 , C07C233/63
CPC分类号： C07C235/40 , A61K31/164 , C07C233/63 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2601/16 , C07C2601/18 , C07C2602/42
摘要： Described herein are compounds that are EP4 agonists and antagonists which are useful for treating a variety of pathological conditions associated with activity of EP4 receptors.
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公开(公告)号：US20220402866A1
公开(公告)日：2022-12-22
申请号：US17545940
申请日：2021-12-08
申请人： Allergan, Inc.
发明人： Christopher D. Hein , Tien T. Duong , Santosh Sinha , Ling Li , Jeremiah H. Nguyen , David W. Old , Robert Burk , Veena Viswanath , Sandhya Rao , John E. Donello
IPC分类号： C07C311/39 , A61P17/06 , C07C237/44 , A61P27/02 , C07C211/52 , C07D307/36 , C07D307/79 , C07D215/42 , C07B59/00 , C07D333/54 , C07C311/43 , A61P29/00
摘要： Described herein are compounds, or pharmaceutically acceptable salts thereof, of the following formula: The compounds are useful for treating inflammatory and autoimmune diseases.
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公开(公告)号：US10407382B2
公开(公告)日：2019-09-10
申请号：US15899867
申请日：2018-02-20
申请人： ALLERGAN, INC.
发明人： David W. Old , Christopher D. Hein
IPC分类号： C07C235/40 , C07C233/63 , A61K31/164
摘要： Described herein are compounds that are EP4 agonists and antagonists which are useful for treating a variety of pathological conditions associated with activity of EP4 receptors.
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公开(公告)号：US20190047947A1
公开(公告)日：2019-02-14
申请号：US16103607
申请日：2018-08-14
申请人： ALLERGAN, INC.
发明人： Christopher D. Hein , Tien T. Duong , Santosh Sinha , Ling Li , Jeremiah H. Nguyen , David W. Old , Robert Burk , Veena Viswanath , Sandhya Rao , John E. Donello
IPC分类号： C07C311/39 , A61P17/06 , A61P27/02 , C07C237/44
摘要： Described herein are compounds, or pharmaceutically acceptable salts thereof, of the following formula: The compounds are useful for treating inflammatory and autoimmune diseases.
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公开(公告)号：US09926262B2
公开(公告)日：2018-03-27
申请号：US15316786
申请日：2015-06-05
申请人： ALLERGAN, INC.
发明人： David W. Old , Christopher D. Hein
IPC分类号： C07C235/40 , C07C233/63
CPC分类号： C07C235/40 , C07C233/63 , C07C2101/08 , C07C2101/10 , C07C2101/14 , C07C2101/16 , C07C2101/18 , C07C2102/42 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2601/16 , C07C2601/18 , C07C2602/42
摘要： Described herein are compounds that are EP4 agonists and antagonists which are useful for treating a variety of pathological conditions associated with activity of EP4 receptors.
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