Patent search ap:("ALMIRALL S.A.") AND inv:"Francesc CARRERA CARRERA" Page 1

1.

发明申请
SALTS OF 2-AMINO-1-HYDROXYETHYL-8-HYDROXYQUINOLIN-2(1H)-ONE DERIVATIVES HAVING BOTH β2 ADRENERGIC RECEPTOR AGONIST AND M3 MUSCARINIC RECEPTOR ANTAGONIST ACTIVITIES 有权
Title translation: 2-氨基-1-羟基乙基-8-羟基喹啉-2（1H） - 酮衍生物，具有两种和两种ADRENERGIC受体激动剂和M3MUSCARINIC受体拮抗剂活性

公开(公告)号：US20160009698A1

公开(公告)日：2016-01-14

申请号：US14770206

申请日：2014-02-27

Applicant: ALMIRALL S.A.

Inventor： Montserrat JULIA JANE , Francesc CARRERA CARRERA , Maria PRAT QUIÑONES , Carlos PUIG DURAN , Francesca PAJUELO LORENZO , Juan Antonio PEREZ ANDRES

IPC: C07D409/14 , C07C309/05 , A61K9/00 , C07C59/255 , A61K31/4709 , A61K45/06 , C07D275/06

CPC classification number: C07D409/14 , A61K9/0073 , A61K9/0075 , A61K31/4709 , A61K45/06 , C07B2200/13 , C07C59/255 , C07C309/05 , C07D275/06 , A61K2300/00

Abstract: The present invention is directed to crystalline addition salts of (i) 8-hydroxyquinolin-2(1H)-one derivatives and (ii) a hydroxycarboxylic acid, a sulfonic acid or a sulfimide, or a pharmaceutically acceptable solvates thereof.

Abstract translation: 本发明涉及（i）8-羟基喹啉-2（1H） - 酮衍生物和（ii）羟基羧酸，磺酸或硫酰亚胺或其药学上可接受的溶剂合物的结晶加成盐。

2.

发明申请
ADDITION SALTS OF (S)-2-(1-(6-AMINO-5-CYANOPYRIMIDIN-4-YLAMINO)ETHYL)-4-OXO-3-PHENYL-3,4-DIHYDROPYRROLO[1,2-F][1,2,4]TRIAZINE-5-CARBONITRILE 审中-公开

公开(公告)号：US20170158699A1

公开(公告)日：2017-06-08

申请号：US15313762

申请日：2015-05-21

Applicant: Almirall, S.A.

Inventor： Francesc CARRERA CARRERA , Juan Bautista PEREZ GARCIA , Bernat VIDAL JUAN , Francisco SANCHEZ IZQUIEROD , Maria Carme SERRA COMA

IPC: C07D487/04 , A61K31/53 , C07C309/30 , C07C309/04 , C07C309/35

CPC classification number: A61K31/53 , A61K31/573 , A61K45/06 , C07B2200/13 , C07C309/04 , C07C309/30 , C07C309/35 , C07D487/04

Abstract: The present invention is directed to novel pharmaceutically acceptable, addition salts of (S)-2-(1-(6-amino-5-cyanopyrimidin-4-ylamino)ethyl)-4-oxo-3-phenyl-3,4-dihydropyrrolo[1,2-f][1,2,4]triazine-5-carbonitrile with sulfonic acid derivatives, in particular with methanesulfonic acid, naphthalene-2-sulfonic acid and para-toluenesulfonic acid, and pharmaceutically acceptable solvates thereof, and their use as Phosphoinositide 3-Kinase (PI3K) inhibitors.

3.

发明申请
SALTS OF 2-AMINO-1-HYDROXYETHYL-8-HYDROXYQUINOLIN-2(1H)-ONE DERIVATIVES HAVING BOTH MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITIES 有权
Title translation: 具有两种MUSCARINIC受体拮抗剂和BETA2 ADRENERGIC受体激动剂活性的2-氨基-1-羟基乙基-8-羟基喹啉-2（1H） - 酮衍生物的盐

公开(公告)号：US20160166566A1

公开(公告)日：2016-06-16

申请号：US14906991

申请日：2014-07-24

Applicant: ALMIRALL, S.A.

Inventor： Montserrat JULIA JANE , Francesc CARRERA CARRERA , Maria PRAT QUIÑONES , Carlos PUIG DURAN , Francesca PAJUELO LORENZO , Juan Antonio PEREZ ANDRES

IPC: A61K31/4709 , A61K9/00 , A61K45/06

CPC classification number: A61K31/4709 , A61K9/0075 , A61K9/008 , A61K31/4725 , A61K45/06 , C07B2200/13 , C07C57/15 , C07D275/06 , C07D409/14 , C07D417/14 , A61K2300/00

Abstract: The present invention is directed to crystalline addition salts of (ii) 8-hydroxyquinolin-2(1H)-one derivatives and (ii) a dicarboxylic acid or a sulfimide, or a pharmaceutically acceptable solvates thereof.

Abstract translation: 本发明涉及（ii）8-羟基喹啉-2（1H） - 酮衍生物和（ii）二羧酸或硫酰亚胺或其药学上可接受的溶剂合物的结晶加成盐。

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