Non-Natural Amino Acid Replication-Dependent Microorganisms and Vaccines
    1.
    发明申请
    Non-Natural Amino Acid Replication-Dependent Microorganisms and Vaccines 有权
    非天然氨基酸复制微生物和疫苗

    公开(公告)号:US20130280301A1

    公开(公告)日:2013-10-24

    申请号:US13936201

    申请日:2013-07-07

    申请人: AMBRX, INC.

    发明人: Feng TIAN Brad HEHLI

    IPC分类号: A61K39/108

    摘要: Compositions and methods of producing vaccines, including methods wherein whole organism vaccines are provided with limited replication abilities, thereby increasing vaccine safety and efficacy, through the use of non-natural, unnatural, or non-naturally encoded amino acids.

    摘要翻译: 制备疫苗的组合物和方法,包括通过使用非天然的,非天然的或非天然编码的氨基酸使整个生物体疫苗具有有限的复制能力,从而增加疫苗安全性和功效的方法。