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公开(公告)号：US20220257864A1
公开(公告)日：2022-08-18
申请号：US17537922
申请日：2021-11-30
Applicant: AMGEN INC.
Inventor： Sivakumar Paramanandam , Andrew Coles , Nicola Antonio Alagia , Antonio Antonini
Abstract: An autoinjector drug delivery device configured with a stall and endpoint detection algorithm is described that allows for variations in the fill of the drug, barrel, plunger, and other components. The stall or end point detection can cause the autoinjector to stop an extrusion process.
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公开(公告)号：US11071826B2
公开(公告)日：2021-07-27
申请号：US16188445
申请日：2018-11-13
Applicant: AMGEN INC.
Inventor： Andrew Coles , Chad Quistad , Emanuele Strada , Francesco Lauritano , Alessia Mazzicone , Antonio Antonini
Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a cassette, a door coupled to the housing, a drive mechanism, and a latching assembly. The cassette is removably disposed within the inner volume and is adapted to contain a drug to be administered to a user. The door at least partially encloses the inner volume of the housing and includes a first end defining a latching portion. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the drug out the cassette. The latching assembly is coupled to the drive mechanism and includes a first end and a second end. Upon actuating the drive mechanism, the drive mechanism causes the latching assembly to engage the latching portion of the door to secure the door to the housing.
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公开(公告)号：US20220362472A1
公开(公告)日：2022-11-17
申请号：US17630207
申请日：2020-07-29
Applicant: AMGEN INC.
Inventor： Azita Rahbari , Sunitha Dasoju , Antonio Antonini , Nicola Antonio Alagia , Angelo Tosarini
IPC: A61M5/24
Abstract: A drug delivery device and related method of operation of a drug delivery device is described that includes a housing, a reservoir removably disposed within the housing and having a sidewall defining an interior for containing a drug, a temperature sensor that is configured to measure a current temperature relating to at least one of the reservoir, the sidewall of the reservoir, the housing, or the drug, and an output device that is configured to output data relating to the current temperature.
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公开(公告)号：US20190143044A1
公开(公告)日：2019-05-16
申请号：US16188496
申请日：2018-11-13
Applicant: AMGEN INC.
Inventor： Sivakumar Paramanandam , Andrew Coles , Nicola Alagia , Antonio Antonini
Abstract: An autoinjector drug delivery device configured with a stall and endpoint detection algorithm is described that allows for variations in the fill of the drug, barrel, plunger, and other components. The stall or end point detection causes the autoinjector to stop an extrusion process.
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Patent Agency Ranking
公开(公告)号：US20240082507A1
公开(公告)日：2024-03-14
申请号：US17767462
申请日：2020-10-07
Applicant: AMGEN INC.
Inventor： Samin Akbari , Azita Rahbari , Sunitha Dasoju , Andrew Coles , Jerome Olivas , Michele Macchi , Desheng Yin , Harpreet Sachar , Alireza Ashani , Angelo Tosarini , Antonio Antonini
IPC: A61M5/32
CPC classification number: A61M5/3257 , A61M5/3213
Abstract: A cassette for a drug delivery device is described that includes a sleeve, a syringe having a barrel disposed in the sleeve, and a plunger-stopper slidably disposed within the barrel. The cassette further includes a spacer that is configured to be coupled to the sleeve. The cassette can form a part of an apparatus for injection of a therapeutic product along with a drug delivery device.
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公开(公告)号：US20190143043A1
公开(公告)日：2019-05-16
申请号：US16188445
申请日：2018-11-13
Applicant: AMGEN INC.
Inventor： Andrew Coles , Chad Quistad , Emanuele Strada , Francesco Lauritano , Alessia Mazzicone , Antonio Antonini
Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a cassette, a door coupled to the housing, a drive mechanism, and a latching assembly. The cassette is removably disposed within the inner volume and is adapted to contain a drug to be administered to a user. The door at least partially encloses the inner volume of the housing and includes a first end defining a latching portion. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the drug out the cassette. The latching assembly is coupled to the drive mechanism and includes a first end and a second end. Upon actuating the drive mechanism, the drive mechanism causes the latching assembly to engage the latching portion of the door to secure the door to the housing.
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公开(公告)号：US20220262505A1
公开(公告)日：2022-08-18
申请号：US17626688
申请日：2020-07-16
Applicant: AMGEN INC.
Inventor： Azita Rahbari , Sunitha Dasoju , Antonio Antonini , NIcola Antonio Alagia , Ferdinando Valenti
Abstract: Drug delivery devices are configured to inject a drug over an injection time within an acceptable range calculated based on information pertaining to the drug to be injected. In particular, drug delivery devices are described that allow identification of the drug to be injected, calculation or determination of an acceptable range of injection times for the identified drug, determination of a tailored injection time within the acceptable range of injection times, and setting of a delivery speed of a drive such that the drug is expelled over the tailored injection time.
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公开(公告)号：US20220184318A1
公开(公告)日：2022-06-16
申请号：US17437615
申请日：2020-04-10
Applicant: AMGEN INC.
Inventor： Azita Rahbari , Sunitha Dasoju , Angelo Tosarini , Antonio Antonini , Julian Jazayeri , Harpreet Sachar , Andrew Coles , Desheng Yin , Alireza Ashani
Abstract: A cassette for a drug delivery device is described that includes a sleeve, a syringe having a barrel disposed in the sleeve, and a plunger-stopper slidably disposed within the barrel. An end cap is adapted to couple to the sleeve to secure the syringe in the sleeve. The cassette further includes a spacer that is sized to be slidably moved within the barrel and the spacer is disposed distal to the plunger-stopper to be engaged by a plunger rod to slide within the barrel and engage the plunger-stopper. In some forms, the spacer can be coupled to the end cap.
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公开(公告)号：US11213626B2
公开(公告)日：2022-01-04
申请号：US16188496
申请日：2018-11-13
Applicant: AMGEN INC.
Inventor： Sivakumar Paramanandam , Andrew Coles , Nicola Alagia , Antonio Antonini
Abstract: An autoinjector drug delivery device configured with a stall and endpoint detection algorithm is described that allows for variations in the fill of the drug, barrel, plunger, and other components. The stall or end point detection causes the autoinjector to stop an extrusion process.
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