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1.发明授权公开(公告)号：US12060430B2
公开(公告)日：2024-08-13
申请号：US17332578
申请日：2021-05-27
申请人： AMGEN INC.
发明人： Junming Yie , Donghui Shi , David J. Lloyd , Jinghong Wang , Glenn N. Sivits, Jr. , Murielle M. Veniant-Ellison , Renee Komorowski , Neeraj Agrawal , Darren L. Bates , Brandon C. P. Clavette , Ian N. Foltz , Shu-yin Ho , Christopher Murawsky , Xiaoshan Min , Zhulun Wang
CPC分类号： C07K16/2869 , A61K9/0019 , A61K38/1703 , A61K38/26 , A61K39/3955 , A61K2039/505 , A61K2039/54 , C07K2299/00 , C07K2317/21 , C07K2317/32 , C07K2317/33 , C07K2317/41 , C07K2317/52 , C07K2317/71 , C07K2317/76 , C07K2317/92 , A61K39/3955 , A61K2300/00
摘要： Methods of treating metabolic diseases and disorders using an antigen binding protein specific for the GIPR polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy. In certain embodiments the antigen binding protein is administered in combination with a GLP-1 receptor agonist.
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公开(公告)号：US11046774B2
公开(公告)日：2021-06-29
申请号：US16285118
申请日：2019-02-25
申请人： AMGEN INC.
发明人： Junming Yie , Donghui Shi , David J. Lloyd , Jinghong Wang , Glenn N. Sivits, Jr. , Murielle M. Veniant-Ellison , Renee Komorowski , Neeraj Agrawal , Darren L. Bates , Brandon C. P. Clavette , Ian N. Foltz , Shu-yin Ho , Christopher Murawsky , Xiaoshan Min , Zhulun Wang
摘要： Methods of treating metabolic diseases and disorders using an antigen binding protein specific for the GIPR polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy. In certain embodiments the antigen binding protein is administered in combination with a GLP-1 receptor agonist.
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公开(公告)号：US20190276546A1
公开(公告)日：2019-09-12
申请号：US16285118
申请日：2019-02-25
申请人： AMGEN INC.
发明人： Junming Yie , Donghui Shi , David J. Lloyd , Jinghong Wang , Glenn N. Sivits, JR. , Murielle M. Veniant-Ellison , Renee Komorowski , Neeraj Agrawal , Darren L. Bates , Brandon C. P. Clavette , Ian N. Foltz , Shu-yin Ho , Christopher Murawsky , Xiaoshan Min , Zhulun Wang
IPC分类号： C07K16/28 , A61K9/00 , A61K38/26 , A61K39/395 , A61K38/17
摘要： Methods of treating metabolic diseases and disorders using an antigen binding protein specific for the GIPR polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy. In certain embodiments the antigen binding protein is administered in combination with a GLP-1 receptor agonist.
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公开(公告)号：US10294303B2
公开(公告)日：2019-05-21
申请号：US15387542
申请日：2016-12-21
申请人： AMGEN INC.
发明人： Junming Yie , Donghui Shi , David J. Lloyd , Jinghong Wang , Glenn N. Sivits, Jr. , Murielle M. Veniant-Ellison , Renee Komorowski , Neeraj Agrawal , Darren L. Bates , Brandon C. P. Clavette , Ian N. Foltz , Shu-yin Ho , Christopher Murawsky , Xiaoshan Min , Zhulun Wang
摘要： Methods of treating metabolic diseases and disorders using an antigen binding protein specific for the GIPR polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy. In certain embodiments the antigen binding protein is administered in combination with a GLP-1 receptor agonist.
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