公开(公告)号：US20240075406A1

公开(公告)日：2024-03-07

申请号：US18268683

申请日：2022-02-17

Applicant: AMGEN INC.

Inventor： Jeremy S. Conner ,  Glenn M. Hunter ,  Kenneth Shoemaker ,  Neil Soice ,  Bret Wylie ,  John B. Flynn ,  Nakorn Kaeonil ,  Thuy N. Nguyen ,  Siddharth Sigh

IPC: B01D15/18 ,  C07K1/16

CPC classification number: B01D15/1885 ,  C07K1/16

Abstract: Parallel chromatography systems and continuous manufacturing methods are described herein that utilize two or more chromatography column skids having columns operating in parallel with automation controls governing which column to load at a given time.

公开(公告)号：US20240051990A1

公开(公告)日：2024-02-15

申请号：US18268772

申请日：2022-03-10

Applicant: AMGEN INC.

Inventor： Neil Soice ,  Jeremy S. Conner ,  Glenn M. Hunter ,  Kenneth Shoemaker ,  Bret Wylie ,  John B. Flynn ,  Nakorn Kaeonil ,  Thuy N. Nguyen ,  Siddharth Singh

IPC: C07K1/36

CPC classification number: C07K1/36

Abstract: Parallel chromatography systems and continuous manufacturing methods are described herein that utilize two or more chromatography column skids having columns operating in parallel with automation controls governing which column to load at a given time.

公开(公告)号：US20240181408A1

公开(公告)日：2024-06-06

申请号：US18285159

申请日：2022-04-14

Applicant: AMGEN INC.

Inventor： Bret Wylie

IPC: B01F33/45 ,  B01F35/32 ,  H01F7/08

CPC classification number: B01F33/45 ,  B01F35/32005 ,  B01F35/3213 ,  H01F7/081

Abstract: A magnetic drive extension may be adapted to be positioned between a magnetic drive that generates a rotating magnetic field and a component, such as an agitator, driven by the magnetic drive, to increase the strength of the magnetic coupling between the drive and component. For example, a mechanical magnetic drive extension may house a rotating shaft around which a rotating magnet mount is configured to rotate, with two oppositely polarized magnets attached to opposite sides of the mount, such that the rotational force causes the rotating magnet mount to rotate, which in turn generates a second rotating magnetic field that causes a second rotational magnetic force to be applied to the component. As another example, a magnetically permeable magnetic drive extension may be comprised of an insulating material in which magnetic conductor components are embedded with even spacing around the interior perimeter of the magnetically permeable magnetic drive extension.

公开(公告)号：US20230204132A1

公开(公告)日：2023-06-29

申请号：US17928320

申请日：2021-05-25

Applicant: AMGEN INC.

Inventor： Kenneth Shoemaker ,  Jonathan Anson ,  Bret Wylie ,  Glenn M. Hunter ,  Sperry K. Brown

IPC: F16L3/10

CPC classification number: F16L3/1091 ,  F16L3/1075

Abstract: A tubing support device for tubing of a drug manufacturing system. The tubing support device has a body having a first end, a second end, and a plurality of projections. The plurality of projections include a first projection disposed at the first end and a second projection disposed at the second end. Each of the first and second projections includes an aperture adapted to receive a fastener. A bore extends from the first end to the second end of the body, and the bore is adapted to receive welded tubing such that the body reinforces the tubing, allowing the tubing to contain fluids at high pressures and/or preventing kinking in the tubing.