公开(公告)号：US20240208680A1

公开(公告)日：2024-06-27

申请号：US18288549

申请日：2022-05-19

Applicant: AMGEN INC.

Inventor： Devrishi Goswami ,  Jun Zhang ,  Deirdre Piedmonte ,  Vikashni Padmakumar ,  David Le ,  Maria Raquel Santos ,  Wei Qi

IPC: B65B3/00 ,  B65B3/12 ,  B65B3/28

CPC classification number: B65B3/003 ,  B65B3/12 ,  B65B3/28

Abstract: A method of filing a vial. The method includes providing a pump corresponding to a vial and setting a drip retraction parameter for the pump to any value equal to or less than 20 degrees. The method also includes setting a no adjustment limit for a fill weight of the vial to T1, with T1 being at or in a range of about 2% more or less than a fill weight of a target fill weight T0, wherein a process performance index Cpk (Cpk) for the vial throughout a fil cycle exceeds a minimum value.