公开(公告)号：US12053618B2

公开(公告)日：2024-08-06

申请号：US16761149

申请日：2018-11-06

Applicant: AMGEN INC.

Inventor： Justin Harris ,  Matthew Wayne Janke ,  Wael Mismar ,  Jerome Olivas ,  Thomas Clark Pearson ,  Sudeshna Dutta Ray ,  Ryan M. Agard ,  Alexis Dechelette ,  Michael Gammelager ,  Mads Hansen ,  Valerio Mazzon ,  Owen Ryan ,  Clive Smith

IPC: A61M5/28 ,  A61M5/178 ,  A61M5/24 ,  A61M5/31

CPC classification number: A61M5/28 ,  A61M5/1782 ,  A61M5/24 ,  A61M5/3134 ,  A61M2005/2488 ,  A61M2005/3115

Abstract: Fill-finish assemblies facilitating the manufacture of a drug delivery device are disclosed. The fill-finish assembly may include a container, an insertion mechanism, a fluid pathway connection assembly disposed between the container and the insertion mechanism, and a carrier. The insertion mechanism may include a delivery member and an insertion mechanism housing. The insertion mechanism may be configured to move the delivery member from a retracted position inside the insertion mechanism housing to a deployed position outside the insertion mechanism housing. The fluid pathway connection assembly may be selectively activatable to establish fluid communication between the container and the delivery member. The carrier may have a hollow interior containing at least a portion of each of the container, the insertion mechanism, and the fluid pathway connection assembly. The carrier may be configured to hold the container, the insertion mechanism, and the fluid pathway connection assembly in alignment with each other.

公开(公告)号：US20200338271A1

公开(公告)日：2020-10-29

申请号：US16761149

申请日：2018-11-06

Applicant: AMGEN INC.

Inventor： Justin Harris ,  Matthew Wayne Janke ,  Wael Mismar ,  Jerome Olivas ,  Thomas Clark Pearson ,  Sudeshna Dutta Ray ,  Ryan M. Agard ,  Alexis Dechelette ,  Michael Gammelager ,  Mads Hansen ,  Valerio Mazzon ,  Owen Ryan ,  Clive Smith

IPC: A61M5/28 ,  A61M5/31 ,  A61M5/24 ,  A61M5/178

Abstract: Fill-finish assemblies facilitating the manufacture of a drug delivery device are disclosed. The fill-finish assembly may include a container, an insertion mechanism, a fluid pathway connection assembly disposed between the container and the insertion mechanism, and a carrier. The insertion mechanism may include a delivery member and an insertion mechanism housing. The insertion mechanism may be configured to move the delivery member from a retracted position inside the insertion mechanism housing to a deployed position outside the insertion mechanism housing. The fluid pathway connection assembly may be selectively activatable to establish fluid communication between the container and the delivery member. The carrier may have a hollow interior containing at least a portion of each of the container, the insertion mechanism, and the fluid pathway connection assembly. The carrier may be configured to hold the container, the insertion mechanism, and the fluid pathway connection assembly in alignment with each other.