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公开(公告)号:US20250099682A1
公开(公告)日:2025-03-27
申请号:US18975470
申请日:2024-12-10
Applicant: AMGEN INC.
Inventor: Emil Finkelstein , Lars Eilertsen , Michael Sorensen , Tobias Maduro Norbo
Abstract: A drug delivery device may include a housing having an opening and a drug storage container having a body portion with a proximal end and a distal end and a delivery member extending from the distal end of the body portion. The device may also include a plunger moveable toward the distal end of the drug storage container to expel a drug from the drug storage container through the delivery member and a plunger biasing member configured to urge the plunger toward the distal end of the drug storage container. The device may further include a container holder configured to support the drug storage container with respect to the housing such that a resultant force acting on the drug storage container from the plunger biasing member is at least substantially completely borne by the distal end of the body portion of the drug storage container.
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公开(公告)号:US20210121633A1
公开(公告)日:2021-04-29
申请号:US17035927
申请日:2020-09-29
Applicant: AMGEN INC.
Inventor: Emil Finkelstein , Lars Eilertsen , Michael Sorensen , Tobias Maduro Norbo
Abstract: A drug delivery device may include a housing having an opening and a drug storage container having a body portion with a proximal end and a distal end and a delivery member extending from the distal end of the body portion. The device may also include a plunger moveable toward the distal end of the drug storage container to expel a drug from the drug storage container through the delivery member and a plunger biasing member configured to urge the plunger toward the distal end of the drug storage container. The device may further include a container holder configured to support the drug storage container with respect to the housing such that a resultant force acting on the drug storage container from the plunger biasing member is at least substantially completely borne by the distal end of the body portion of the drug storage container.
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公开(公告)号:US20210093789A1
公开(公告)日:2021-04-01
申请号:US17036556
申请日:2020-09-29
Applicant: AMGEN INC.
Inventor: Christian Plambech , Matias Melander , Bjarke Lykke Ludvig Svendsen , Joshua Jay Dudman , Michael Sorensen , Margaux Frances Boyaval , Avon Kuo
Abstract: Drug delivery devices and related arrangements are disclosed. A drug delivery device may include a housing having an opening, a drug storage container including a delivery member with an insertion end configured to extend at least partially through the opening, and a plunger. A drive mechanism may be included for driving the plunger in a distal direction to expel a drug from the drug storage container through the delivery member upon activation. The drug delivery device may additionally include a guard moveably disposed adjacent to the opening and operably coupled to the drive mechanism for activation of the drive mechanism. A lock may be selectively engageable with the guard to limit movement of the guard in the proximal direction. An indicator may be coupled to the drive mechanism to generate an audible signal during drug delivery, and to cease generating the audible signal when drug delivery is complete.
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公开(公告)号:US12208245B2
公开(公告)日:2025-01-28
申请号:US17035927
申请日:2020-09-29
Applicant: AMGEN INC.
Inventor: Emil Finkelstein , Lars Eilertsen , Michael Sorensen , Tobias Maduro Norbo
Abstract: A drug delivery device may include a housing having an opening and a drug storage container having a body portion with a proximal end and a distal end and a delivery member extending from the distal end of the body portion. The device may also include a plunger moveable toward the distal end of the drug storage container to expel a drug from the drug storage container through the delivery member and a plunger biasing member configured to urge the plunger toward the distal end of the drug storage container. The device may further include a container holder configured to support the drug storage container with respect to the housing such that a resultant force acting on the drug storage container from the plunger biasing member is at least substantially completely borne by the distal end of the body portion of the drug storage container.
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公开(公告)号:US20240390599A1
公开(公告)日:2024-11-28
申请号:US18789085
申请日:2024-07-30
Applicant: AMGEN INC.
Inventor: Christian Plambech , Matias Melander , Bjarke Lykke Ludvig Svendsen , Joshua Jay Dudman , Michael Sorensen , Margaux Frances Boyaval , Avon Kuo
Abstract: Drug delivery devices and related arrangements are disclosed. A drug delivery device may include a housing having an opening, a drug storage container including a delivery member with an insertion end configured to extend at least partially through the opening, and a plunger. A drive mechanism may be included for driving the plunger in a distal direction to expel a drug from the drug storage container through the delivery member upon activation. The drug delivery device may additionally include a guard moveably disposed adjacent to the opening and operably coupled to the drive mechanism for activation of the drive mechanism. A lock may be selectively engageable with the guard to limit movement of the guard in the proximal direction. An indicator may be coupled to the drive mechanism to generate an audible signal during drug delivery, and to cease generating the audible signal when drug delivery is complete.
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公开(公告)号:US12102808B2
公开(公告)日:2024-10-01
申请号:US17036556
申请日:2020-09-29
Applicant: AMGEN INC.
Inventor: Christian Plambech , Matias Melander , Bjarke Lykke Ludvig Svendsen , Joshua Jay Dudman , Michael Sorensen , Margaux Frances Boyaval , Avon Kuo
CPC classification number: A61M5/3157 , A61M5/2033 , A61M5/3204 , A61M2205/581
Abstract: Drug delivery devices and related arrangements are disclosed. A drug delivery device may include a housing having an opening, a drug storage container including a delivery member with an insertion end configured to extend at least partially through the opening, and a plunger. A drive mechanism may be included for driving the plunger in a distal direction to expel a drug from the drug storage container through the delivery member upon activation. The drug delivery device may additionally include a guard moveably disposed adjacent to the opening and operably coupled to the drive mechanism for activation of the drive mechanism. A lock may be selectively engageable with the guard to limit movement of the guard in the proximal direction. An indicator may be coupled to the drive mechanism to generate an audible signal during drug delivery, and to cease generating the audible signal when drug delivery is complete.
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公开(公告)号:US20210093796A1
公开(公告)日:2021-04-01
申请号:US17036217
申请日:2020-09-29
Applicant: AMGEN INC.
Inventor: Emil Finkelstein , Lars Eilertsen , Michael Sorensen , Tobias Maduro Norbo
Abstract: A drug delivery device may include a housing having an opening and a drug storage container including a delivery member having an insertion end configured to extend at least partially through the opening during a delivery state. The device may also include a guard moveably positioned adjacent to the opening and a plunger having a generally cylindrical body portion extending along a longitudinal axis of the container and at least one flange extending radially outwardly from the body portion, wherein the plunger is moveable toward the distal end of the container to expel a drug through the delivery member. The device may further include a plunger biasing member configured to urge the plunger toward the distal end of the container and a releaser member defining a guide configured to receive the at least one flange and an indicator configured to generate an audible signal indicating an end of drug delivery.
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