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    EXTERNAL COMPOSITION FOR SKIN CONTAINING MANASSANTIN B AS ACTIVE INGREDIENT AND THE USE THEREOF FOR SKIN WHITENING
    1.
    发明申请
    EXTERNAL COMPOSITION FOR SKIN CONTAINING MANASSANTIN B AS ACTIVE INGREDIENT AND THE USE THEREOF FOR SKIN WHITENING 审中-公开
    含有作为活性成分的马尼松丁B的皮肤外用组合物及其用于皮肤白化的用途

    公开(公告)号：US20130303605A1

    公开(公告)日：2013-11-14

    申请号：US13939807

    申请日：2013-07-11

    Applicant: Amorepacific Corporation

    Inventor： Hui Kyoung CHANG ,  Dae Gun KIM ,  Myeong Hoon YEOM ,  Hyun Jung CHOI ,  Kyung Mi JOO ,  Jae Sung HWANG ,  Soo Mi AHN

    IPC: A61K8/49 ,  A61Q19/02

    CPC classification number: A61K8/4973 ,  A61K31/343 ,  A61Q19/02

    Abstract: Disclosed herein are an external composition for skin, which contains, as an active ingredient, manassantin B extracted from Saururus chinensis Baill, and the use thereof for skin whitening. More particularly, disclosed are an external composition for skin, which contains, as an active ingredient, manassantin B, which inhibits the transfer of melanosomes, thus providing a skin-whitening effect without influencing the melanin synthesis function of the melanocytes, as well as the use thereof for skin whitening.

    Abstract translation: 本发明公开了一种皮肤外用组合物，其含有作为活性成分的从中华黄ensis提取的马桑丁B及其用于皮肤美白的用途。 更具体地，公开了一种皮肤外用组合物，其含有抑制黑素体转移的马桑丁汀B作为活性成分，从而提供皮肤美白效果而不影响黑素细胞的黑色素合成功能，以及 其用于皮肤美白。

    METHOD FOR QUANTIFYING SKIN CHANGES CAUSED BY SIX EXTERNAL EVILS AND METHOD FOR SCREENING SKIN CONDITION-IMPROVING MATERIALS USING THE SAME
    2.
    发明申请
    METHOD FOR QUANTIFYING SKIN CHANGES CAUSED BY SIX EXTERNAL EVILS AND METHOD FOR SCREENING SKIN CONDITION-IMPROVING MATERIALS USING THE SAME 审中-公开
    用于定量六种外部因素引起的皮肤变化的方法和使用其来筛选皮肤状况的方法 - 改善材料

    公开(公告)号：US20140377756A1

    公开(公告)日：2014-12-25

    申请号：US14478733

    申请日：2014-09-05

    Applicant: AMOREPACIFIC CORPORATION

    Inventor： Jin Young LEE ,  Sun Sang KWON ,  Myeong Hoon YEOM ,  Duck Hee KIM ,  Han Kon KIM

    IPC: G01N33/53 ,  C12Q1/02 ,  C12Q1/30 ,  C12Q1/68 ,  C12Q1/32

    CPC classification number: G01N33/53 ,  C12Q1/02 ,  C12Q1/30 ,  C12Q1/32 ,  C12Q1/68 ,  C12Q1/686 ,  G01N33/5044 ,  G01N2500/04

    Abstract: A method for quantifying skin changes caused by six external evils and a method of screening skin condition-improving materials using the quantification method are described. More specifically, disclosed are a method of measuring cellular changes caused by external stimuli in a skin cell culture system, in which the degree of cellular changes obtained by applying suitable stimuli of six external evils to skin cells being cultured is measured by cellular biochemical methods, such that the conceptual effects of six external evils suggested in the prior art can be scientifically and quantitatively expressed, and a method of screening skin condition-improving materials using the measurement method.

    Abstract translation: 描述了一种用于量化由六种外部损害引起的皮肤变化的方法和使用定量方法筛选皮肤状况改善材料的方法。 更具体地，公开了测量皮肤细胞培养系统中由外部刺激引起的细胞变化的方法，其中通过细胞生物化学方法测量通过对正在培养的皮肤细胞施加六种外部恶性的合适刺激而获得的细胞变化程度， 使得现有技术中提出的六种外部邪恶的概念效应可以被科学地和定量地表达，以及使用测量方法筛选皮肤状况改善材料的方法。

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