公开(公告)号：US20140377756A1

公开(公告)日：2014-12-25

申请号：US14478733

申请日：2014-09-05

Applicant: AMOREPACIFIC CORPORATION

Inventor： Jin Young LEE ,  Sun Sang KWON ,  Myeong Hoon YEOM ,  Duck Hee KIM ,  Han Kon KIM

IPC: G01N33/53 ,  C12Q1/02 ,  C12Q1/30 ,  C12Q1/68 ,  C12Q1/32

CPC classification number: G01N33/53 ,  C12Q1/02 ,  C12Q1/30 ,  C12Q1/32 ,  C12Q1/68 ,  C12Q1/686 ,  G01N33/5044 ,  G01N2500/04

Abstract: A method for quantifying skin changes caused by six external evils and a method of screening skin condition-improving materials using the quantification method are described. More specifically, disclosed are a method of measuring cellular changes caused by external stimuli in a skin cell culture system, in which the degree of cellular changes obtained by applying suitable stimuli of six external evils to skin cells being cultured is measured by cellular biochemical methods, such that the conceptual effects of six external evils suggested in the prior art can be scientifically and quantitatively expressed, and a method of screening skin condition-improving materials using the measurement method.

Abstract translation: 描述了一种用于量化由六种外部损害引起的皮肤变化的方法和使用定量方法筛选皮肤状况改善材料的方法。 更具体地，公开了测量皮肤细胞培养系统中由外部刺激引起的细胞变化的方法，其中通过细胞生物化学方法测量通过对正在培养的皮肤细胞施加六种外部恶性的合适刺激而获得的细胞变化程度， 使得现有技术中提出的六种外部邪恶的概念效应可以被科学地和定量地表达，以及使用测量方法筛选皮肤状况改善材料的方法。

公开(公告)号：US20160220622A1

公开(公告)日：2016-08-04

申请号：US15093089

申请日：2016-04-07

Applicant: AMOREPACIFIC CORPORATION

Inventor： Jun Seong PARK ,  Hye Yoon PARK ,  Dong Hyun KIM ,  Eun Jeong MOON ,  Ji Hye CHUNG ,  Jae Kyoung LEE ,  Duck Hee KIM ,  Han Kon KIM

IPC: A61K36/185

CPC classification number: A61K36/185 ,  A23L33/105 ,  A23V2002/00 ,  A61K36/232 ,  A61K36/28 ,  A61K36/287 ,  A61K36/428 ,  A61K36/45 ,  A61K36/732 ,  A61K36/78 ,  A61K36/8945

Abstract: The present invention relates to an extract of a processed herbal medicinal plant and a composition for skin external application which contains the extract. More specifically, the composition for skin external application contains an extract of processed herbal medicinal plant, prepared through a method comprising the steps of: (a) processing an herbal medicinal plant by a process of boiling, steaming, roasting, baking or heating the medicinal plant or a combination of two or more of these processes; (b) obtaining an extract of the processed medicinal plant. The composition shows an improved antioxidant effect.

Abstract translation: 本发明涉及含有该提取物的加工草药植物提取物和皮肤外用组合物。 更具体地，皮肤外用组合物含有通过包括以下步骤的方法制备的加工草药植物提取物：（a）通过沸腾，蒸煮，焙烧，烘烤或加热药物的方法加工中草药植物 植物或两种或更多种这些方法的组合; （b）获得加工药用植物的提取物。 该组合物显示出改进的抗氧化作用。

公开(公告)号：US20150184216A1

公开(公告)日：2015-07-02

申请号：US14588790

申请日：2015-01-02

Applicant: AMOREPACIFIC CORPORATION

Inventor： Jun Seong PARK ,  Duck Hee KIM ,  Han Kon KIM ,  Eun Mi KIM ,  Byung Gee KIM

IPC: C12P33/20 ,  C12P17/06

CPC classification number: C12P33/20 ,  C12N1/20 ,  C12N9/0004 ,  C12P17/06 ,  C12P19/02 ,  C12P33/00 ,  C12R1/41 ,  Y02P20/52

Abstract: The present invention relates to the novel Rhizobium sp. GIN611 KCTC11708BP or to cell extracts thereof, to a novel oxidoreductase which exhibits a glycolytic activity, to a gene encoding the oxidoreductase, to a recombinant strain comprising recombinant vector proteins or to an expression vector encoding recombinant proteins, and to a method for the glycolysis of natural products using same as a biocatalyst. The present invention also relates to a method for producing aglycones from a variety of natural products using same. The novel oxidoreductase separated from the novel microorganism of the present invention does not belong to a glucosidase group but belongs to an oxidoreductase group, and has a glycolytic activity for natural products. The novel oxidoreductase oxidizes the sugar in the aglycones of natural products, thereby producing a variety of aglycones.

Abstract translation: 本发明涉及新根瘤菌属（Rhizobium sp。） GIN611KCTC11708BP或其细胞提取物，对具有糖酵解活性的新型氧化还原酶，与编码该氧化还原酶的基因相连，包含重组载体蛋白的重组菌株或编码重组蛋白的表达载体，以及糖酵解方法 使用与生物催化剂相同的天然产物。 本发明还涉及使用它们的各种天然产物制备糖苷配基的方法。 从本发明的新型微生物分离的新型氧化还原酶不属于葡萄糖苷酶基团，属于氧化还原酶基团，对天然产物具有糖酵解活性。 新型氧化还原酶氧化天然产物的糖苷配基中的糖，从而产生各种糖苷配基。

公开(公告)号：US20140341827A1

公开(公告)日：2014-11-20

申请号：US14450349

申请日：2014-08-04

Applicant: AMOREPACIFIC CORPORATION

Inventor： Sun Sang KWON ,  Myeong Hun YEOM ,  Duck Hee KIM ,  Han Kon KIM ,  Nok Hyun PARK ,  Soo Mi AHN

IPC: A61K8/73 ,  A61Q19/08 ,  A61Q19/00 ,  A61K8/97 ,  A61Q19/02

CPC classification number: A61K8/73 ,  A61K8/97 ,  A61K2800/74 ,  A61K2800/782 ,  A61Q19/007 ,  A61Q19/02 ,  A61Q19/08

Abstract: Disclosed is a method for preparing polysaccharides of green tea, and more particularly to a method for preparing polysaccharides of green tea comprising the steps of: a) removing chlorophyll and a low molecular weight polyphenol from green tea powder using a solvent; b) hot-water extracting a water-soluble active ingredient from the green tea residue of step a); and c) separating the polysaccharides of green tea from the hot-water extract of step b) by ultrafiltration and ethanol precipitation. Also, the present invention relates to a cosmetic composition for skin whitening, moisturization and anti-wrinkle effects comprising the polysaccharides of green tea as an effective ingredient.

Abstract translation: 公开了一种制备绿茶多糖的方法，更具体地说，涉及一种制备绿茶多糖的方法，包括以下步骤：a）使用溶剂从绿茶粉中除去叶绿素和低分子量多酚; b）从步骤a）的绿茶残渣中热水提取水溶性活性成分; 和c）通过超滤和乙醇沉淀从绿茶的多糖分离步骤b）的热水提取物。 另外，本发明涉及包含绿茶多糖作为有效成分的皮肤美白，保湿和抗皱效果的化妆品组合物。