公开(公告)号：US20210177919A1

公开(公告)日：2021-06-17

申请号：US16759892

申请日：2018-10-05

Applicant: AMOREPACIFIC CORPORATION

Inventor： Eun-Gyung CHO ,  Wanil KIM ,  Tae Ryong LEE

IPC: A61K35/747 ,  A61K8/14 ,  A23L33/135 ,  A61K8/99

Abstract: The present specification discloses an immunomodulatory composition comprising Lactobacillus-derived extracellular vesicles as an active ingredient. The Lactobacillus may be Lactobacillus plantarum. The composition has the effects of inducing differentiation into M2-type macrophages and reducing expression of at least one member selected from the group consisting of CCR2, SOCS3 and HLA-DRα, which are M1-type macrophage differentiation markers.