公开(公告)号：US20220000734A1

公开(公告)日：2022-01-06

申请号：US17285214

申请日：2019-10-15

Applicant: AMOREPACIFIC CORPORATION

Inventor： Eun Jeong CHOI ,  Hyoung-June KIM ,  Tae Ryong LEE ,  Hyunjung CHOI

IPC: A61K8/365 ,  A61Q19/00 ,  A61Q17/00

Abstract: Provided are a composition including a compound of the following chemical formula as an active ingredient and a method of strengthening the skin barrier by applying it to skin of a subject:

公开(公告)号：US20200230186A1

公开(公告)日：2020-07-23

申请号：US16651880

申请日：2018-08-20

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyoung-June KIM ,  Tae Ryong LEE

IPC: A61K36/185 ,  A61K8/9789 ,  A61Q19/00 ,  A23L33/105

Abstract: Disclosed is a composition including a Hibiscus syriacus extract as an effective ingredient for treating fine dust-caused skin damage, wherein the expression of at least one selected from the group consisting of IL-36G (NM_019618), PTGS2 (NM_000963), XDH (NM_000379) and S100A7 (NM_002963), which are all genes having the expression levels affected by fine dust in skin cells, is regulated to a normal level and for inhibiting an antibacterial peptide, wherein the expression of the antibacterial peptide S100A7 (NM_002963) is regulated to a normal level. By using the composition for treating fine dust-caused skin damage and the composition for inhibiting an antibacterial peptide, gene expression changed by fine dust can return to a normal level to treat skin cell damage and the increased expression of the antibacterial peptide due to various causes can return to normal level.

公开(公告)号：US20180369114A1

公开(公告)日：2018-12-27

申请号：US16014677

申请日：2018-06-21

Applicant: AMOREPACIFIC CORPORATION

Inventor： Kyu-Han KIM ,  Hyoung-June KIM ,  Tae Ryong LEE

IPC: A61K8/64 ,  A61Q5/08 ,  A61Q19/02

Abstract: The present specification is intended to develop a new substance which exhibits a skin whitening effect and to apply the new substance to a composition for skin whitening, provides a new composition for skin whitening and a new kit for skin whitening which contain TNFSF14 protein and a polynucleotide encoding the TNFSF14 protein and a method of using the same, and thus can contribute to the market expansion and industry development related to the skin whitening field.

公开(公告)号：US20170304175A1

公开(公告)日：2017-10-26

申请号：US15521570

申请日：2015-11-27

Applicant: AMOREPACIFIC CORPORATION

Inventor： Eun Kyung LEE ,  Myeong Jin GOH ,  Hyun Jung CHOI ,  Eun Gyung CHO ,  Tae Ryong LEE

IPC: A61K8/49 ,  A61Q5/00 ,  A61Q19/08

CPC classification number: A61K8/498 ,  A61K8/49 ,  A61K31/352 ,  A61K31/353 ,  A61K2800/78 ,  A61K2800/91 ,  A61Q5/00 ,  A61Q19/00 ,  A61Q19/08

Abstract: The present disclosure discloses a novel use of genistein, epigallocatechin gallate (EGCG), derivatives thereof, isomers thereof, pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates thereof and solvates thereof. A composition containing genistein, epigallocatechin gallate, derivatives thereof isomers thereof, pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates thereof or solvates thereof reduces the expression of factors related to increase of melanin producing ability, reduces the expression of senescence marker proteins and regulates the expression of enzymes involved in melanin production, and thus may have an effect of rejuvenating cells including melanocytes.

公开(公告)号：US20210338553A1

公开(公告)日：2021-11-04

申请号：US17280947

申请日：2019-11-29

Applicant: Amorepacific Corporation

Inventor： Il Hong BAE ,  Gibaeg NAM ,  Jaeyoung KO ,  Jaewon YOU ,  Tae Ryong LEE

IPC: A61K8/35 ,  A61Q17/04 ,  A61Q19/08

Abstract: A cosmetic composition includes a compound of the following chemical formula as an active ingredient. A method for regenerating skin includes applying an effective amount of the cosmetic composition to skin: wherein R1 to R7 are independently a substituted or unsubstituted C1 to C20 alkyl group.

公开(公告)号：US20200345694A1

公开(公告)日：2020-11-05

申请号：US16759211

申请日：2018-07-24

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyun Jung CHOI ,  Hyoung June KIM ,  Ji Yong JUNG ,  Tae Ryong LEE

IPC: A61K31/4035 ,  A61K31/4436 ,  A61K36/06 ,  A61K8/49 ,  A61K8/9728 ,  A23L33/10 ,  A61Q19/08

Abstract: The present disclosure relates to an antiaging composition containing cytochalasin D or SAG, and a method for screening an antiaging substance, and provides a new antiaging substance and a new method for discovering a new antiaging substance. Thus, it is possible to greatly contribute to the development of beauty industries and to meeting demands related with beauty and antiaging, if the present disclosure is effectively used.

公开(公告)号：US20180256488A1

公开(公告)日：2018-09-13

申请号：US15760882

申请日：2016-09-26

Applicant: AMOREPACIFIC CORPORATION

Inventor： Eun-Jeong CHOI ,  Yonghee LEE ,  Seung Hyun SHIN ,  Kyeonghwan HWANG ,  Eun-Gyung CHO ,  Tae Ryong LEE

IPC: A61K8/9789 ,  A61Q7/00

CPC classification number: A61K8/9789 ,  A61K8/14 ,  A61K36/258 ,  A61Q7/00

Abstract: Disclosed in the present specification are: a composition for preventing hair loss or promoting hair growth, containing ginseng-derived exosome-like vesicles; and a method for preparing the composition. The ginseng-derived exosome-like vesicles can have a diameter of 20-500 nm and can be isolated from ginseng root. The composition contains ginseng-derived exosome-like vesicles as active ingredients, thereby having an effect of inducing hair growth by activating dermal papilla cells (DPCs).

公开(公告)号：US20170231900A1

公开(公告)日：2017-08-17

申请号：US15514600

申请日：2015-09-24

Applicant: AMOREPACIFIC CORPORATION

Inventor： Pil Joon PARK ,  Seung Hyun SHIN ,  Hae Kwang LEE ,  Jon Hwan LEE ,  Tae Ryong LEE ,  Eun Gyung CHO

IPC: A61K8/97 ,  A23L2/52 ,  A23L33/105 ,  A61K8/34 ,  A61Q7/00

CPC classification number: A61K8/97 ,  A23L2/52 ,  A23L33/105 ,  A23V2002/00 ,  A61K8/34 ,  A61K36/539 ,  A61Q7/00

Abstract: Disclosed is a novel use of a composition comprising as an active ingredient a Scutellaria alpina extract. A composition according to the present description shows hair follicle cell proliferation or hair growth effect by means of comprising a Scutellaria alpina extract. Therefore, due to said effect, the Scutellaria alpina extract has hair loss prevention or hair growth stimulation effect.

公开(公告)号：US20170216386A1

公开(公告)日：2017-08-03

申请号：US15514617

申请日：2015-09-24

Applicant: AMOREPACIFIC CORPORATION

Inventor： Pil Joon PARK ,  Seung Hyun SHIN ,  Hae Kwang LEE ,  Jon Hwan LEE ,  Tae Ryong LEE ,  Eun Gyung CHO

IPC: A61K36/539 ,  A61K9/00 ,  A61K47/10

CPC classification number: A61K36/539 ,  A61K8/97 ,  A61K9/0014 ,  A61K9/0019 ,  A61K9/08 ,  A61K9/1623 ,  A61K9/1652 ,  A61K9/2018 ,  A61K9/205 ,  A61K9/4858 ,  A61K9/4866 ,  A61K36/282 ,  A61K47/10 ,  A61Q7/00

Abstract: Disclosed is a novel use of a composition comprising as an active ingredient an Artemisia umbelliformis extract. A composition according to the present description shows hair follicle cell proliferation or hair growth effect by means of comprising an Artemisia umbelliformis extract. Therefore, due to said effect, the Artemisia umbelliformis extract has hair loss prevention or hair growth stimulation effect.

公开(公告)号：US20170105926A1

公开(公告)日：2017-04-20

申请号：US15301417

申请日：2015-04-02

Applicant: AMOREPACIFIC CORPORATION

Inventor： Pil Joon PARK ,  So Hee LEE ,  Eun Gyung CHO ,  Tae Ryong LEE

IPC: A61K8/97 ,  A61Q19/00 ,  A61K9/48 ,  A61K9/20 ,  A23L33/16 ,  A23L2/52 ,  A23L33/105 ,  A23L33/15 ,  A23L33/155 ,  A61K36/282 ,  A61K9/00

CPC classification number: A61K8/97 ,  A23L2/52 ,  A23L33/105 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A23V2002/00 ,  A61K9/0095 ,  A61K9/20 ,  A61K9/48 ,  A61K36/282 ,  A61K2800/782 ,  A61K2800/92 ,  A61Q19/00

Abstract: Disclosed is a composition comprising an extract of alpine wormwood (Artemisia umbelliformis) as an active ingredient. The composition disclosed in the present specification, which comprises the extract of alpine wormwood (Artemisia umbelliformis), exhibits an effect of reducing the amount of endothelin 1 and reducing the overexpression of NK1R and EDN1 genes. Accordingly, due to such effects, the alpine wormwood (Artemisia umbelliformis) extract of the present disclosure can exhibit benefits for maintaining skin homeostasis as well as an anti-stress effect, and thus can be widely used in pharmaceutical or cosmetic fields as a composition for maintaining skin homeostasis.