公开(公告)号：US20230124095A1

公开(公告)日：2023-04-20

申请号：US17909549

申请日：2021-01-28

Applicant: AMORPHICAL LTD.

Inventor： Yossi BEN ,  Yigal BLUM ,  Yehudit NATAN

IPC: A61K33/10 ,  A61K9/00 ,  A61K31/728 ,  A61P29/00 ,  A61P35/00 ,  A61P11/00 ,  A61P31/14 ,  A61K9/16

Abstract: The preset invention is directed to ACC particles stabilized by at least one stabilizing agent, a pharmaceutical composition including same, and methods of using same, such as for treating or preventing an acidosis-related disease or condition in a subject in need thereof.

公开(公告)号：US20240018009A1

公开(公告)日：2024-01-18

申请号：US18227077

申请日：2023-07-27

Applicant: AMORPHICAL LTD.

Inventor： Yossi BEN ,  Yigal BLUM ,  Roni Antoine ILLOS ,  Ben ASHKENAZI

IPC: C01F5/24 ,  C01F11/18 ,  C01G9/00 ,  A61K33/10 ,  A61K33/30 ,  A61K33/42 ,  A61K9/16 ,  A61K9/10

CPC classification number: C01F5/24 ,  C01F11/18 ,  C01G9/00 ,  A61K33/10 ,  A61K33/30 ,  A61K33/42 ,  C01P2002/02 ,  A61K9/10 ,  C01P2004/03 ,  C01P2004/62 ,  C01P2004/64 ,  C01P2006/12 ,  A61K9/16

Abstract: The present invention provides a composition including a particle, the particle includes a carbonate species of a first divalent metal and carbonate specie of a second divalent metal; wherein the particle is amorphous; wherein the first divalent metal and the second divalent metal are in an oxidation state of +2; and wherein the first divalent metal and the second divalent metal is each independently selected from: Ca, Zn, Fe, Cu, Co, Ni, Mn, Mg and Cr. Further provided is a composition including a divalent metal carbonate including any derivative thereof, and at least one stabilizing agent, wherein the divalent metal is selected from: Zn, Cu, Co, Mn, Mg, and Ni, optionally being characterized by BET between 20 and 200 m2/g. Pharmaceutical or nutraceutical compositions including the composition of particles disclosed, are also provided.