公开(公告)号：US11903961B2

公开(公告)日：2024-02-20

申请号：US17404688

申请日：2021-08-17

申请人： AMRITA VISHWA VIDYAPEETHAM

发明人： Jayakumar Rangasamy ,  Nivedhitha Muthiahpillai Sundaram ,  Ullas Mony ,  Praveen Kerala Varma

IPC分类号： A61K31/722 ,  A61K33/06 ,  A61P7/04 ,  A61L26/00 ,  C08J3/075

CPC分类号： A61K31/722 ,  A61K33/06 ,  A61L26/008 ,  A61L26/0023 ,  A61L26/0095 ,  A61P7/04 ,  C08J3/075 ,  A61L2400/04 ,  C08J2305/08

摘要： A composition and method of preparing the composition for rapid and effective hemostasis is provided. The composition includes a first agent to induce platelet plug formation, a second to induce vasoconstriction and a third agent for activation of coagulation cascade. The composition comprises of 0.01% to 5% of chitosan; 0.01% to 0.25% of potassium aluminum sulphate; and 0.01% to 0.25% calcium salt. The clotting time of the composition is in the range of 30s to 140s. A method of preparing the hemostatic composition is further disclosed. The composition is configured to control hemorrhage from oozing and pressured bleeding injury any site in human/animal body.