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公开(公告)号：US20190282604A1
公开(公告)日：2019-09-19
申请号：US16068243
申请日：2017-01-06
IPC分类号： A61K31/713 , A61K31/4375 , A61K31/18 , A61K31/5377 , A61K31/675 , A61P31/20 , A61K31/7068 , A61K31/352
摘要： The invention provides therapeutic combinations and therapeutic methods that are useful for treating Hepatitis B.
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公开(公告)号：US20220168430A1
公开(公告)日：2022-06-02
申请号：US17440480
申请日：2020-03-19
发明人： Andrzej ARDZINSKI , Andrea CUCONATI , Amy C. H. LEE , Nagraj MANI , Cornelis A. RIJNBRAND , Michael J. SOFIA , Emily P. THI
IPC分类号： A61K47/55 , A61K47/60 , A61K38/21 , A61K31/675 , A61K31/522 , A61K31/4196 , A61K31/4375 , A61K31/7088 , A61K47/54 , A61P31/20
摘要： The invention provides therapeutic combinations and therapeutic methods that are useful for treating Hepatitis B and Hepatitis D.
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公开(公告)号：US20240052349A1
公开(公告)日：2024-02-15
申请号：US18035695
申请日：2021-11-05
发明人： Owen M. DALY , Amy C. H. LEE , Michael J. SOFIA , Emily P. THI
IPC分类号： C12N15/113 , A61K47/54 , A61K45/06 , A61P31/20
CPC分类号： C12N15/1131 , A61K47/549 , A61K45/06 , A61P31/20
摘要： The invention provides certain nucleic acids (e.g., double stranded siRNA molecules), as well as conjugates that comprise a targeting moiety, an siRNA, and optional linking groups. The conjugates are useful to target siRNA.
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公开(公告)号：US20240050463A1
公开(公告)日：2024-02-15
申请号：US18071353
申请日：2022-11-29
IPC分类号： A61K31/713 , A61P31/20 , A61K31/18 , A61K31/352 , A61K31/4375 , A61K31/5377 , A61K31/675 , A61K31/7068
CPC分类号： A61K31/713 , A61P31/20 , A61K31/18 , A61K31/352 , A61K45/06 , A61K31/5377 , A61K31/675 , A61K31/7068 , A61K31/4375
摘要： The invention provides therapeutic combinations and therapeutic methods that are useful for treating Hepatitis B.
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