公开(公告)号：US12031981B2

公开(公告)日：2024-07-09

申请号：US17053522

申请日：2019-05-08

Applicant: Arizona Board of Regents on behalf of Arizona State University

Inventor： Stuart Lindsay ,  Bintian Zhang

IPC: G01N27/327 ,  G01N33/487 ,  G01N33/543 ,  G01N33/68

CPC classification number: G01N33/5438 ,  G01N33/48721 ,  G01N33/6854 ,  G01N2469/20

Abstract: The present disclosure relates to a sensing device and methods for detecting, and quantifying the amount of, a target protein in a sample.

公开(公告)号：US20220389502A1

公开(公告)日：2022-12-08

申请号：US17832316

申请日：2022-06-03

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Stuart Lindsay ,  Eathen Ryan ,  Bintian Zhang ,  Xu Wang

IPC: C12Q1/6869 ,  C12Q1/00 ,  G01N27/12

Abstract: The present disclosure provides devices, systems, and methods related to sequencing a biopolymer. In particular, the present disclosure relates to methods for sequencing a polynucleotide using a bioelectronic device that includes protein assemblies used as coupling molecules in bioelectronic circuits. The present disclosure also provides multimeric protein assemblies with various combinations of live and dead subunits arranged to maximize conduction.

公开(公告)号：US20220098635A1

公开(公告)日：2022-03-31

申请号：US17426893

申请日：2020-01-30

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Stuart Lindsay ,  Bintian Zhang ,  Hanqing Deng

IPC: C12Q1/00

Abstract: A universal connection system for assembling and electrically connecting proteins to make bioelectronic detectors and logic circuits, exploiting the electronic properties of ligand-receptor interactions and the quasi metallic properties of protein interiors.