公开(公告)号：US20220389502A1

公开(公告)日：2022-12-08

申请号：US17832316

申请日：2022-06-03

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Stuart Lindsay ,  Eathen Ryan ,  Bintian Zhang ,  Xu Wang

IPC: C12Q1/6869 ,  C12Q1/00 ,  G01N27/12

Abstract: The present disclosure provides devices, systems, and methods related to sequencing a biopolymer. In particular, the present disclosure relates to methods for sequencing a polynucleotide using a bioelectronic device that includes protein assemblies used as coupling molecules in bioelectronic circuits. The present disclosure also provides multimeric protein assemblies with various combinations of live and dead subunits arranged to maximize conduction.

公开(公告)号：US20220196646A1

公开(公告)日：2022-06-23

申请号：US17553392

申请日：2021-12-16

Applicant: Arizona Board of Regents on behalf of Arizona State University

Inventor： Stuart Lindsay ,  Eathen Ryan

IPC: G01N33/543 ,  G01N27/04

Abstract: The present disclosure provides devices, systems, and methods related to protein bioelectronics. In particular, the present disclosure provides devices, systems, and methods for forming electrical contacts to a protein with high yield, which facilitates the manufacture of analytical devices to detect and measure the electrical characteristics corresponding to protein function.