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公开(公告)号:US20160326181A1
公开(公告)日:2016-11-10
申请号:US15152823
申请日:2016-05-12
申请人: AbbVie Inc.
发明人: Neil Wishart , Maria A. Argiriadi , David J. Calderwood , Anna M. Ericsson , Bryan R. Fiamengo , Kristine E. Frank , Michael M. Friedman , Dawn M. George , Eric R. Goedken , Nathan S. Josephsohn , Biqin C. Li , Michael J. Morytko , Kent D. Stewart , Jeffrey W. Voss , Grier A. Wallace , Lu Wang , Kevin R. Woller
IPC分类号: C07D487/14
CPC分类号: C07D487/14 , C07D498/14 , C07D513/14
摘要: The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
摘要翻译: 药学上可接受的盐,前药,生物活性代谢物,立体异构体和异构体,其中变量在本文中定义。 本发明的化合物可用于治疗免疫学和肿瘤学病症。
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公开(公告)号:US09365579B2
公开(公告)日:2016-06-14
申请号:US14610119
申请日:2015-01-30
申请人: AbbVie Inc.
发明人: Neil Wishart , Maria A. Argiriadi , David J. Calderwood , Anna M. Ericsson , Bryan A. Fiamengo , Kristine E. Frank , Michael M. Friedman , Dawn M. George , Eric R. Goedken , Nathan S. Josephsohn , Biqin C. Li , Michael J. Morytko , Kent D. Stewart , Jeffrey W. Voss , Grier A. Wallace , Lu Wang , Kevin R. Woller
IPC分类号: C07D487/14 , C07D498/14 , C07D513/14
CPC分类号: C07D487/14 , C07D498/14 , C07D513/14
摘要: The invention provide a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomer and isomer thereof wherein the variable are defined herein. The compound of the invention are useful for treating immunological and oncological conditions.
摘要翻译: 本发明提供式(I)化合物,其药学上可接受的盐,前药,生物活性代谢物,立体异构体和异构体,其中变量在本文中定义。 本发明的化合物可用于治疗免疫和肿瘤病症。
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公开(公告)号:US20150297596A1
公开(公告)日:2015-10-22
申请号:US14696680
申请日:2015-04-27
申请人: ABBVIE INC.
发明人: David J. Calderwood , Eric C. Breinlinger , Steven L. Swann , Subhendu Mukherjee , Venkata Srikanth Chitty , Siva Sanjeeva Rao Thunuguntla , Subramanya Seetharama Shastry Hosahalli
IPC分类号: A61K31/506 , A61K31/541 , A61K31/5377
CPC分类号: A61K31/506 , A61K31/5377 , A61K31/541 , C07D413/04 , C07D413/12 , C07D413/14 , Y02A50/401 , Y02A50/463 , Y02A50/481
摘要: The present invention provides compound of Formula (I) biologically active metabolites, pro-drugs, isomers, stereoisomers, solvates, hydrates and pharmaceutically acceptable salts thereof wherein the variables are defined herein. The compounds of the invention are useful for treating immunological conditions.
摘要翻译: 本发明提供式(I)化合物的生物活性代谢物,前药,异构体,立体异构体,溶剂合物,水合物及其药学上可接受的盐,其中变量在本文中定义。 本发明的化合物可用于治疗免疫学病症。
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公开(公告)号:US20160222020A1
公开(公告)日:2016-08-04
申请号:US15017802
申请日:2016-02-08
申请人: AbbVie Inc.
发明人: Neil Wishart , Maria A. Argiriadi , David J. Calderwood , Anna M. Ericsson , Bryan A. Fiamengo , Kristine E. Frank , Michael M. Friedman , Dawn M. George , Eric R. Goedken , Nathan S. Josephsohn , Biqin C. Li , Michael J. Morytko , Kent D. Stewart , Jeffrey W. Voss , Grier A. Wallace , Lu Wang , Kevin R. Woller
IPC分类号: C07D487/14 , A61K31/437 , C07D471/14 , A61K31/4985 , A61K45/06
CPC分类号: C07D487/14 , A61K31/437 , A61K31/4985 , A61K45/06 , C07D471/14 , C07D498/14 , C07D513/14
摘要: The invention provides compounds of Formula (I) and Formula (II) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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公开(公告)号:US20150210708A1
公开(公告)日:2015-07-30
申请号:US14610119
申请日:2015-01-30
申请人: AbbVie Inc.
发明人: Neil Wishart , Maria A. Argiriadi , David J. Calderwood , Anna M. Ericsson , Bryan A. Fiamengo , Kristine E. Frank , Michael M. Friedman , Dawn M. George , Eric R. Goedken , Nathan S. Josephsohn , Biqin C. Li , Michael J. Morytko , Kent D. Stewart , Jeffrey W. Voss , Grier A. Wallace , Lu Wang , Kevin R. Woller
IPC分类号: C07D487/14
CPC分类号: C07D487/14 , C07D498/14 , C07D513/14
摘要: The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
摘要翻译: 本发明提供式(I)化合物的药学上可接受的盐,前药,生物活性代谢物,立体异构体和异构体,其中变量在本文中定义。 本发明的化合物可用于治疗免疫学和肿瘤学病症。
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公开(公告)号:US20180291029A1
公开(公告)日:2018-10-11
申请号:US15806104
申请日:2017-11-07
申请人: AbbVie Inc.
发明人: Neil WISHART , Maria A. Argiriadi , David J. Calderwood , Anna M. Ericsson , Bryan R. Fiamengo , Kristine E. Frank , Michael M. Friedman , Dawn M. George , Eric R. Goedken , Nathan S. Josephsohn , Biqin C. Li , Michael J. Morytko , Kent D. Stewart , Jeffrey W. Voss , Grier A. Wallace , Lu Wang , Kevin R. Woller
IPC分类号: C07D487/14 , C07D513/14 , C07D498/14
摘要: The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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