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公开(公告)号:US20180291029A1
公开(公告)日:2018-10-11
申请号:US15806104
申请日:2017-11-07
申请人: AbbVie Inc.
发明人: Neil WISHART , Maria A. Argiriadi , David J. Calderwood , Anna M. Ericsson , Bryan R. Fiamengo , Kristine E. Frank , Michael M. Friedman , Dawn M. George , Eric R. Goedken , Nathan S. Josephsohn , Biqin C. Li , Michael J. Morytko , Kent D. Stewart , Jeffrey W. Voss , Grier A. Wallace , Lu Wang , Kevin R. Woller
IPC分类号: C07D487/14 , C07D513/14 , C07D498/14
摘要: The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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公开(公告)号:US20160326181A1
公开(公告)日:2016-11-10
申请号:US15152823
申请日:2016-05-12
申请人: AbbVie Inc.
发明人: Neil Wishart , Maria A. Argiriadi , David J. Calderwood , Anna M. Ericsson , Bryan R. Fiamengo , Kristine E. Frank , Michael M. Friedman , Dawn M. George , Eric R. Goedken , Nathan S. Josephsohn , Biqin C. Li , Michael J. Morytko , Kent D. Stewart , Jeffrey W. Voss , Grier A. Wallace , Lu Wang , Kevin R. Woller
IPC分类号: C07D487/14
CPC分类号: C07D487/14 , C07D498/14 , C07D513/14
摘要: The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
摘要翻译: 药学上可接受的盐,前药,生物活性代谢物,立体异构体和异构体,其中变量在本文中定义。 本发明的化合物可用于治疗免疫学和肿瘤学病症。
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公开(公告)号:US08642776B2
公开(公告)日:2014-02-04
申请号:US13627753
申请日:2012-09-26
申请人: AbbVie Inc.
发明人: Yujia Dai , Steven K. Davidsen , Anna M. Ericsson , Kresna Hartandi , Zhiqin Ji , Michael R. Michaelides
IPC分类号: C07D275/04
CPC分类号: C07D231/56 , C07D261/20 , C07D275/04 , C07D401/04 , C07D401/10 , C07D401/12 , C07D403/12 , C07D403/14 , C07D409/04 , C07D409/10 , C07D409/12 , C07D409/14 , C07D413/12
摘要: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
摘要翻译: 具有该式的化合物可用于抑制蛋白酪氨酸激酶。 本发明还公开了制备化合物的方法,含有该化合物的组合物和使用该化合物的处理方法。
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公开(公告)号:US09365579B2
公开(公告)日:2016-06-14
申请号:US14610119
申请日:2015-01-30
申请人: AbbVie Inc.
发明人: Neil Wishart , Maria A. Argiriadi , David J. Calderwood , Anna M. Ericsson , Bryan A. Fiamengo , Kristine E. Frank , Michael M. Friedman , Dawn M. George , Eric R. Goedken , Nathan S. Josephsohn , Biqin C. Li , Michael J. Morytko , Kent D. Stewart , Jeffrey W. Voss , Grier A. Wallace , Lu Wang , Kevin R. Woller
IPC分类号: C07D487/14 , C07D498/14 , C07D513/14
CPC分类号: C07D487/14 , C07D498/14 , C07D513/14
摘要: The invention provide a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomer and isomer thereof wherein the variable are defined herein. The compound of the invention are useful for treating immunological and oncological conditions.
摘要翻译: 本发明提供式(I)化合物,其药学上可接受的盐,前药,生物活性代谢物,立体异构体和异构体,其中变量在本文中定义。 本发明的化合物可用于治疗免疫和肿瘤病症。
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公开(公告)号:US20230082167A1
公开(公告)日:2023-03-16
申请号:US17575731
申请日:2022-01-14
申请人: AbbVie Inc.
发明人: Neil WISHART , Maria A. ARGIRIADI , David J. CALDERWOOD , Anna M. Ericsson , Bryan A. FIAMENGO , Kristine E. FRANK , Michael M. FRIEDMAN , Dawn M. GEORGE , Eric R. GOEDKEN , Nathan S. JOSEPHSOHN , Biqin C. LI , Michael J. MORYTKO , Kent D. STEWART , Jeffrey W. VOSS , Grier A. WALLACE , Lu WANG , Kevin R. WOLLER
IPC分类号: C07D487/14 , C07D498/14 , C07D513/14
摘要: The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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公开(公告)号:US20160222020A1
公开(公告)日:2016-08-04
申请号:US15017802
申请日:2016-02-08
申请人: AbbVie Inc.
发明人: Neil Wishart , Maria A. Argiriadi , David J. Calderwood , Anna M. Ericsson , Bryan A. Fiamengo , Kristine E. Frank , Michael M. Friedman , Dawn M. George , Eric R. Goedken , Nathan S. Josephsohn , Biqin C. Li , Michael J. Morytko , Kent D. Stewart , Jeffrey W. Voss , Grier A. Wallace , Lu Wang , Kevin R. Woller
IPC分类号: C07D487/14 , A61K31/437 , C07D471/14 , A61K31/4985 , A61K45/06
CPC分类号: C07D487/14 , A61K31/437 , A61K31/4985 , A61K45/06 , C07D471/14 , C07D498/14 , C07D513/14
摘要: The invention provides compounds of Formula (I) and Formula (II) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
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公开(公告)号:US20150210708A1
公开(公告)日:2015-07-30
申请号:US14610119
申请日:2015-01-30
申请人: AbbVie Inc.
发明人: Neil Wishart , Maria A. Argiriadi , David J. Calderwood , Anna M. Ericsson , Bryan A. Fiamengo , Kristine E. Frank , Michael M. Friedman , Dawn M. George , Eric R. Goedken , Nathan S. Josephsohn , Biqin C. Li , Michael J. Morytko , Kent D. Stewart , Jeffrey W. Voss , Grier A. Wallace , Lu Wang , Kevin R. Woller
IPC分类号: C07D487/14
CPC分类号: C07D487/14 , C07D498/14 , C07D513/14
摘要: The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
摘要翻译: 本发明提供式(I)化合物的药学上可接受的盐,前药,生物活性代谢物,立体异构体和异构体,其中变量在本文中定义。 本发明的化合物可用于治疗免疫学和肿瘤学病症。
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公开(公告)号:US08940778B2
公开(公告)日:2015-01-27
申请号:US13886448
申请日:2013-05-03
申请人: AbbVie Inc.
发明人: Yujia Dai , Steven K Davidsen , Anna M. Ericsson , Kresna Hartandi , Zhiqin Ji , Michael R. Michaelides
IPC分类号: C07D291/00 , C07D409/10 , C07D409/04 , C07D401/12 , C07D261/20 , C07D409/12 , C07D403/12 , C07D409/14 , C07D275/04 , C07D401/04 , C07D401/10 , C07D413/12 , C07D403/14 , C07D231/56
CPC分类号: C07D231/56 , C07D261/20 , C07D275/04 , C07D401/04 , C07D401/10 , C07D401/12 , C07D403/12 , C07D403/14 , C07D409/04 , C07D409/10 , C07D409/12 , C07D409/14 , C07D413/12
摘要: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
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