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公开(公告)号:US20240024338A1
公开(公告)日:2024-01-25
申请号:US18334738
申请日:2023-06-14
Applicant: AbbVie Inc.
Inventor: Benoit Cardinal-David , Vincent S. Chan , Kassibla E. Dempah , Brian P. Enright , Rodger F. Henry , Raimundo Ho , Ye Huang , Alexander D. Huters , Russell C. Klix , Scott W. Krabbe , Philip R. Kym , Yanbin Lao. , Xiaochun Lou , Sean Mackey , Mark A. Matulenko , Peter T. Mayer , Christopher P. Miller , James Stambuli , Valentino J. Stella , Eric A. Voight , Zhi Wang , Geoff G. Zhang
CPC classification number: A61K31/661 , A61K9/0019 , A61K9/14 , A61K45/06 , A61K9/08 , C07F9/12
Abstract: The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
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公开(公告)号:US11542239B2
公开(公告)日:2023-01-03
申请号:US16519443
申请日:2019-07-23
Applicant: AbbVie Inc.
Inventor: Niharika Chauhan , Raimundo Ho , Albert Kruger , Samrat Mukherjee , Stephen T. Chau , Erika Crane , Alex Fabian , Sanjay Chemburkar , Travis Dunn
IPC: C07D239/54
Abstract: The present invention relates to compositions of elagolix sodium, and process and intermediates for the preparation thereof.
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公开(公告)号:US20180079762A1
公开(公告)日:2018-03-22
申请号:US15715245
申请日:2017-09-26
Applicant: AbbVie Inc.
Inventor: Benoit Cardinal-David , Vincent S. Chan , Kassibla Dempah , Brian P. Enright , Rodger F. Henry , Raimundo Ho , Ye Huang , Alexander D. Huters , Russell C. Klix , Scott W. Krabbe , Philip R. Kym , Yanbin Lao , Xiaochun Lou , Sean E. Mackey , Mark A. Matulenko , Peter T. Mayer , Christopher P. Miller , James Stambuli , Eric A. Voight , Zhi Wang , Geoff G. Zhang , Valentino J. Stella
IPC: C07F9/09 , A61K31/661 , C07F9/06 , A61K45/06 , C07C47/277 , C07C309/24 , C07C281/02 , A61K31/6615
CPC classification number: C07F9/094 , A61K31/661 , A61K31/6615 , A61K45/06 , C07B2200/13 , C07C47/277 , C07C281/02 , C07C309/24 , C07F9/06 , A61K2300/00
Abstract: The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
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公开(公告)号:US09446059B2
公开(公告)日:2016-09-20
申请号:US14919418
申请日:2015-10-21
Applicant: AbbVie Inc.
Inventor: Benoit Cardinal-David , Vincent S. Chan , Kassibla E. Dempah , Brian P. Enright , Rodger F. Henry , Raimundo Ho , Ye Huang , Alexander D. Huters , Russell C. Klix , Scott W. Krabbe , Philip R. Kym , Yanbin Lao , Xiaochun Lou , Sean E. Mackey , Mark A. Matulenko , Peter T. Mayer , Christopher P. Miller , James Stambuli , Eric A. Voight , Zhi Wang , Geoff G. Zhang , Valentino J. Stella
IPC: A61K31/661 , C07F9/06 , A61K31/6615
CPC classification number: C07F9/094 , A61K31/661 , A61K31/6615 , A61K45/06 , C07B2200/13 , C07C47/277 , C07C281/02 , C07C309/24 , C07F9/06 , A61K2300/00
Abstract: The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
Abstract translation: 本公开内容涉及(a)卡比多巴前药,(b)药物组合和包含卡比多巴前药和/或左旋多巴前药的组合物,和(c)治疗帕金森病和相关病症的方法,包括施用卡比多巴前药和 左旋多巴前药与帕金森病患者。
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公开(公告)号:US20220324816A1
公开(公告)日:2022-10-13
申请号:US17659269
申请日:2022-04-14
Applicant: AbbVie Inc.
Inventor: Niharika Chauhan , Raimundo Ho , Albert Kruger , Samrat Mukherjee , Stephen T. Chau , Erika Crane , Alex Fabian , Sanjay Chemburkar , Travis Dunn
IPC: C07D239/54
Abstract: The present invention relates to compositions of elagolix sodium, and process and intermediates for the preparation thereof.
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公开(公告)号:US20200262852A1
公开(公告)日:2020-08-20
申请号:US16866400
申请日:2020-05-04
Applicant: AbbVie Inc.
Inventor: Benoit Cardinal-David , Vincent S. Chan , Kassibla E. Dempah , Brian P. Enright , Rodger F. Henry , Raimundo Ho , Ye Huang , Alexander D. Huters , Russell C. Klix , Scott W. Krabbe , Philip R. Kym , Yanbin Lao , Xiaochun Lou , Sean E. Mackey , Mark A. Matulenko , Peter T. Mayer , Christopher P. Miller , James Stambuli , Valentino J. Stella , Eric A. Voight , Zhi Wang , Geoff Zhang
IPC: C07F9/09 , A61K45/06 , A61K31/6615 , C07C47/277 , C07C309/24 , C07C281/02 , C07F9/06 , A61K31/661
Abstract: The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
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公开(公告)号:US20200024239A1
公开(公告)日:2020-01-23
申请号:US16519443
申请日:2019-07-23
Applicant: AbbVie Inc.
Inventor: Niharika Chauhan , Raimundo Ho , Albert Kruger , Samrat Mukherjee , Stephen T. Chau , Erika Crane , Alex Fabian , Sanjay Chemburkar , Travis Dunn
IPC: C07D239/54
Abstract: The present invention relates to compositions of elagolix sodium, and process and intermediates for the preparation thereof.
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公开(公告)号:US20250084042A1
公开(公告)日:2025-03-13
申请号:US18953666
申请日:2024-11-20
Applicant: AbbVie Inc.
Inventor: Niharika Chauhan , Raimundo Ho , Albert Kruger , Samrat Mukherjee , Stephen T. Chau , Erika Crane , Alex Fabian , Sanjay Chemburkar , Travis Dunn
IPC: C07D239/54
Abstract: The present invention relates to compositions of elagolix sodium, and process and intermediates for the preparation thereof.
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公开(公告)号:US20220153765A1
公开(公告)日:2022-05-19
申请号:US17378321
申请日:2021-07-16
Applicant: AbbVie Inc.
Inventor: Benoit Cardinal-David , Vincent S. Chan , Kassibla Dempah , Brian P. Enright , Rodger F. Henry , Raimundo Ho , Ye Huang , Alexander D. Huters , Russell C. Klix , Scott W. Krabbe , Philip R. Kym , Yanbin Lao , Xiaochun Lou , Sean E. Mackey , Mark A. Matulenko , Peter T. Mayer , Christopher P. Miller , James Stambuli , Valentino J. Stella , Eric A. Voight , Zhi Wang , Geoff G. Zhang
IPC: C07F9/09 , A61K31/661 , C07F9/06 , C07C281/02 , C07C309/24 , C07C47/277 , A61K31/6615 , A61K45/06
Abstract: The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
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公开(公告)号:US20190375770A1
公开(公告)日:2019-12-12
申请号:US16210996
申请日:2018-12-05
Applicant: AbbVie Inc.
Inventor: Benoit Cardinal-David , Vincent S. Chan , Kassibla E. Dempah , Brian P. Enright , Rodger F. Henry , Raimundo Ho , Ye Huang , Alexander D. Huters , Russell C. Klix , Scott W. Krabbe , Philip R. Kym , Yanbin Lao , Xiaochun Lou , Sean E. Mackey , Mark A. Matulenko , Peter T. Mayer , Christiopher P. Miller , James Stambuli , Valentino J. Stella , Eric A. Voight , Zhi Wang , Geoff G. Zhang
IPC: C07F9/09 , A61K31/661 , C07F9/06 , C07C281/02 , C07C309/24 , C07C47/277 , A61K31/6615 , A61K45/06
Abstract: The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
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