-
公开(公告)号：US20240024338A1
公开(公告)日：2024-01-25
申请号：US18334738
申请日：2023-06-14
Applicant: AbbVie Inc.
Inventor： Benoit Cardinal-David , Vincent S. Chan , Kassibla E. Dempah , Brian P. Enright , Rodger F. Henry , Raimundo Ho , Ye Huang , Alexander D. Huters , Russell C. Klix , Scott W. Krabbe , Philip R. Kym , Yanbin Lao. , Xiaochun Lou , Sean Mackey , Mark A. Matulenko , Peter T. Mayer , Christopher P. Miller , James Stambuli , Valentino J. Stella , Eric A. Voight , Zhi Wang , Geoff G. Zhang
CPC classification number: A61K31/661 , A61K9/0019 , A61K9/14 , A61K45/06 , A61K9/08 , C07F9/12
Abstract: The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
-
公开(公告)号：US20140303369A1
公开(公告)日：2014-10-09
申请号：US14312006
申请日：2014-06-23
Applicant: AbbVie Inc.
Inventor： Daniel A. Dickman , Sanjay Chemburkar , James J. Fort , Rodger F. Henry , David Lechuga-Ballesteros , Yuping Niu , William R. Porter
IPC: C07D239/10
CPC classification number: C07D239/10 , A61K9/4866 , A61K31/00 , A61K31/513 , A61K47/10 , A61K47/44 , A61K2300/00
Abstract: New crystalline forms of lopinavir are disclosed.
Abstract translation: 公开了新的结晶形式的洛匹那韦。
-
公开(公告)号：US20230183236A1
公开(公告)日：2023-06-15
申请号：US17995874
申请日：2021-04-09
Applicant: AbbVie Inc.
Inventor： Rodger F. Henry , Yi SHI , Geoff Zhang , Devalina Law
IPC: C07D471/04
CPC classification number: C07D471/04 , C07B2200/13
Abstract: Crystalline forms of 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}-sulfonyl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide (Venetoclax) are suitable active pharmaceutical ingredients for pharmaceutical compositions useful in treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.
-
公开(公告)号：US20200262852A1
公开(公告)日：2020-08-20
申请号：US16866400
申请日：2020-05-04
Applicant: AbbVie Inc.
Inventor： Benoit Cardinal-David , Vincent S. Chan , Kassibla E. Dempah , Brian P. Enright , Rodger F. Henry , Raimundo Ho , Ye Huang , Alexander D. Huters , Russell C. Klix , Scott W. Krabbe , Philip R. Kym , Yanbin Lao , Xiaochun Lou , Sean E. Mackey , Mark A. Matulenko , Peter T. Mayer , Christopher P. Miller , James Stambuli , Valentino J. Stella , Eric A. Voight , Zhi Wang , Geoff Zhang
IPC: C07F9/09 , A61K45/06 , A61K31/6615 , C07C47/277 , C07C309/24 , C07C281/02 , C07F9/06 , A61K31/661
Abstract: The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
-
公开(公告)号：US20220153765A1
公开(公告)日：2022-05-19
申请号：US17378321
申请日：2021-07-16
Applicant: AbbVie Inc.
Inventor： Benoit Cardinal-David , Vincent S. Chan , Kassibla Dempah , Brian P. Enright , Rodger F. Henry , Raimundo Ho , Ye Huang , Alexander D. Huters , Russell C. Klix , Scott W. Krabbe , Philip R. Kym , Yanbin Lao , Xiaochun Lou , Sean E. Mackey , Mark A. Matulenko , Peter T. Mayer , Christopher P. Miller , James Stambuli , Valentino J. Stella , Eric A. Voight , Zhi Wang , Geoff G. Zhang
IPC: C07F9/09 , A61K31/661 , C07F9/06 , C07C281/02 , C07C309/24 , C07C47/277 , A61K31/6615 , A61K45/06
Abstract: The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
-
Patent Agency Ranking
公开(公告)号：US20190375770A1
公开(公告)日：2019-12-12
申请号：US16210996
申请日：2018-12-05
Applicant: AbbVie Inc.
Inventor： Benoit Cardinal-David , Vincent S. Chan , Kassibla E. Dempah , Brian P. Enright , Rodger F. Henry , Raimundo Ho , Ye Huang , Alexander D. Huters , Russell C. Klix , Scott W. Krabbe , Philip R. Kym , Yanbin Lao , Xiaochun Lou , Sean E. Mackey , Mark A. Matulenko , Peter T. Mayer , Christiopher P. Miller , James Stambuli , Valentino J. Stella , Eric A. Voight , Zhi Wang , Geoff G. Zhang
IPC: C07F9/09 , A61K31/661 , C07F9/06 , C07C281/02 , C07C309/24 , C07C47/277 , A61K31/6615 , A61K45/06
Abstract: The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
-
公开(公告)号：US20150158867A1
公开(公告)日：2015-06-11
申请号：US14624517
申请日：2015-02-17
Applicant: AbbVie Inc.
Inventor： Michael R. Schrimpf , Diana L. Nersesian , Kevin B. Sippy , Jianguo Ji , Tao Li , Marc Scanio , Lei Shi , Chih-Hung Lee , William H. Bunnelle , Geoff G.Z. Zhang , Paul J. Brackemeyer , Shuang Chen , Rodger F. Henry
IPC: C07D471/18 , A61K31/439 , A61K31/501 , A61K31/444 , C07C309/29 , A61K31/095
CPC classification number: C07D471/18 , A61K31/095 , A61K31/439 , A61K31/444 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/506 , A61K45/06 , C07C309/29 , C07D451/14 , C07D471/08 , C07F5/022
Abstract: The invention relates to compounds that are azaadamantane derivatives, particularly ether- or amine-substituted azaadamantane derivatives and salts and prodrugs thereof, compositions comprising such compounds, methods of using such compounds and compositions, processes for preparing such compounds, and intermediates obtained during such processes.
Abstract translation: 本发明涉及作为氮杂金刚烷衍生物的化合物，特别是醚取代或胺取代的氮杂金刚烷衍生物及其盐和前体药物，包含这些化合物的组合物，使用这些化合物和组合物的方法，制备这些化合物的方法以及在此过程中获得的中间体 。
-
公开(公告)号：US08987453B2
公开(公告)日：2015-03-24
申请号：US13653192
申请日：2012-10-16
Applicant: AbbVie Inc.
Inventor： Michael R. Schrimpf , Diana L. Nersesian , Kevin B. Sippy , Jianguo Ji , Tao Li , Marc Scanio , Lei Shi , Chih-Hung Lee , William H. Bunnelle , Geoff G. Z. Zhang , Paul J. Brackemeyer , Shuang Chen , Rodger F. Henry
IPC: C07D471/18 , A61K45/06 , A61K31/444 , C07D471/08 , C07F5/02 , A61K31/439 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/506
CPC classification number: C07D471/18 , A61K31/095 , A61K31/439 , A61K31/444 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/506 , A61K45/06 , C07C309/29 , C07D451/14 , C07D471/08 , C07F5/022
Abstract: The invention relates to compounds that are azaadamantane derivatives, particularly ether- or amine-substituted azaadamantane derivatives and salts and prodrugs thereof, compositions comprising such compounds, methods of using such compounds and compositions, processes for preparing such compounds, and intermediates obtained during such processes.
Abstract translation: 本发明涉及作为氮杂金刚烷衍生物的化合物，特别是醚取代或胺取代的氮杂金刚烷衍生物及其盐和前体药物，包含这些化合物的组合物，使用这些化合物和组合物的方法，制备这些化合物的方法以及在此过程中获得的中间体 。
-
公开(公告)号：US20130096132A1
公开(公告)日：2013-04-18
申请号：US13653192
申请日：2012-10-16
Applicant: AbbVie Inc.
Inventor： Michael R. Schrimpf , Diana L. Nersesian , Kevin B. Sippy , Jianguo Ji , Tao Li , Marc Scanio , Lei Shi , Chih-Hung Lee , William H. Bunnelle , Geoff G.Z. Zhang , Paul J. Brackemeyer , Shuang Chen , Rodger F. Henry
IPC: C07D471/18 , A61K45/06 , A61K31/501 , A61K31/496 , A61K31/506 , A61K31/497 , A61K31/439 , A61K31/444
CPC classification number: C07D471/18 , A61K31/095 , A61K31/439 , A61K31/444 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/506 , A61K45/06 , C07C309/29 , C07D451/14 , C07D471/08 , C07F5/022
Abstract: The invention relates to compounds that are azaadamantane derivatives, particularly ether- or amine-substituted azaadamantane derivatives and salts and prodrugs thereof, compositions comprising such compounds, methods of using such compounds and compositions, processes for preparing such compounds, and intermediates obtained during such processes.
-
公开(公告)号：US20180079762A1
公开(公告)日：2018-03-22
申请号：US15715245
申请日：2017-09-26
Applicant: AbbVie Inc.
Inventor： Benoit Cardinal-David , Vincent S. Chan , Kassibla Dempah , Brian P. Enright , Rodger F. Henry , Raimundo Ho , Ye Huang , Alexander D. Huters , Russell C. Klix , Scott W. Krabbe , Philip R. Kym , Yanbin Lao , Xiaochun Lou , Sean E. Mackey , Mark A. Matulenko , Peter T. Mayer , Christopher P. Miller , James Stambuli , Eric A. Voight , Zhi Wang , Geoff G. Zhang , Valentino J. Stella
IPC: C07F9/09 , A61K31/661 , C07F9/06 , A61K45/06 , C07C47/277 , C07C309/24 , C07C281/02 , A61K31/6615
CPC classification number: C07F9/094 , A61K31/661 , A61K31/6615 , A61K45/06 , C07B2200/13 , C07C47/277 , C07C281/02 , C07C309/24 , C07F9/06 , A61K2300/00
Abstract: The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
-
-
-
-
-
-
-
-
-
Search Results
11
records
(took 0.029 seconds)
