公开(公告)号：US10072040B2

公开(公告)日：2018-09-11

申请号：US14643858

申请日：2015-03-10

Applicant: AbbVie Inc.

Inventor： Thomas W. von Geldern ,  Dale J. Kempf ,  Kennan C. Marsh

IPC: C07H17/08 ,  A61K31/7048

CPC classification number: C07H17/08 ,  A61K31/7048

Abstract: The present invention pertains to derivatives of tylosin A. In particular, the present invention pertains to compounds having a structure of Formula (I). The present invention also pertains to compositions comprising derivatives of tylosin A and methods of treating or preventing conditions or disorders using such compounds and compositions.

公开(公告)号：US20150259374A1

公开(公告)日：2015-09-17

申请号：US14643858

申请日：2015-03-10

Applicant: AbbVie Inc.

Inventor： Thomas W. von Geldern ,  Dale J. Kempf ,  Kennan C. Marsh

IPC: C07H17/08

CPC classification number: C07H17/08 ,  A61K31/7048

Abstract: The present invention pertains to derivatives of tylosin A. In particular, the present invention pertains to compounds having a structure of Formula (I). The present invention also pertains to compositions comprising derivatives of tylosin A and methods of treating or preventing conditions or disorders using such compounds and compositions.

Abstract translation: 本发明涉及泰乐菌素A的衍生物。特别地，本发明涉及具有式（I）结构的化合物。 本发明还涉及包含泰乐菌素A衍生物的组合物以及使用这些化合物和组合物治疗或预防病症或障碍的方法。

公开(公告)号：US20160200757A1

公开(公告)日：2016-07-14

申请号：US15065337

申请日：2016-03-09

Applicant: AbbVie Inc.

Inventor： Thomas W. von Geldern ,  Dale J. Kempf ,  Kennan C. Marsh

IPC: C07H17/08

CPC classification number: C07H17/08 ,  A61K31/7048

Abstract: The present invention pertains to derivatives of tylosin A. In particular, the present invention pertains to compounds having a structure of Formula (I). The present invention also pertains to compositions comprising derivatives of tylosin A and methods of treating or preventing conditions or disorders using such compounds and compositions.